STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dred_1731TIGRFAM: putative delta-1-pyrroline-5-carboxylate dehydrogenase; PFAM: aldehyde dehydrogenase; KEGG: gka:GK0187 aldehyde dehydrogenase. (514 aa)    
Predicted Functional Partners:
Dred_2805
PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: bha:BH1728 glutamate synthase (large subunit).
  
 
 0.948
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
 
 
 0.926
Dred_1148
PFAM: aminotransferase, class I and II; KEGG: pca:Pcar_1888 aspartate aminotransferase.
   
 0.919
Dred_1696
L-aspartate aminotransferase apoenzyme; PFAM: aminotransferase, class I and II; KEGG: mta:Moth_1490 aminotransferase, class I and II.
   
 0.919
Dred_2965
Pyruvate formate-lyase; KEGG: gsu:GSU2101 formate acetyltransferase; TIGRFAM: pyruvate formate-lyase; PFAM: formate C-acetyltransferase glycine radical; pyruvate formate-lyase, PFL.
  
 
 0.914
Dred_1071
Sulfide dehydrogenase (flavoprotein) subunit SudA; TIGRFAM: glutamate synthase (NADPH), homotetrameric; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: chy:CHY_1991 glutamate synthase (NADPH), homotetrameric.
    
 0.910
proA
Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
   
 
 0.910
proB
Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
   
 
 0.910
Dred_2804
TIGRFAM: glutamate synthases, NADH/NADPH, small subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; HI0933 family protein; KEGG: syn:sll1027 NADH-dependent glutamate synthase small subunit.
    
 0.910
Dred_2969
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: pca:Pcar_2295 probable glutamate synthase small chain.
    
 0.910
Your Current Organism:
Desulfotomaculum reducens
NCBI taxonomy Id: 349161
Other names: D. reducens MI-1, Desulfotomaculum reducens MI-1, Desulfotomaculum reducens str. MI-1, Desulfotomaculum reducens strain MI-1
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