Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Dred_1985TIGRFAM: DNA protecting protein DprA; PFAM: SMF family protein; KEGG: mta:Moth_1025 DNA processing protein DprA, putative. (364 aa)    
Predicted Functional Partners:
Dred_3081
PFAM: phosphoribosyltransferase; KEGG: swo:Swol_0188 phosphoribosyltransferase.
 
 
 0.907
Dred_2510
TIGRFAM: DNA internalization-related competence protein ComEC/Rec2; PFAM: beta-lactamase domain protein; ComEC/Rec2-related protein; KEGG: mta:Moth_0575 DNA internalization-related competence protein ComEC/Rec2.
 
  
 0.897
Dred_2023
Mg chelatase, subunit ChlI; KEGG: mta:Moth_1022 Mg chelatase-related protein; TIGRFAM: Mg chelatase, subunit ChlI; PFAM: magnesium chelatase, ChlI subunit; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase.
 
 0.875
Dred_3008
PFAM: magnesium chelatase, ChlI subunit; KEGG: tte:TTE1455 predicted ATPase with chaperone activity.
 
 0.865
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
 0.844
Dred_1047
Type 4 prepilin peptidase 1, Aspartic peptidase, MEROPS family A24A; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.
  
  
 0.760
Dred_2035
PFAM: protein of unknown function UPF0102; KEGG: tte:TTE1452 predicted endonuclease distantly related to archaeal Holliday junction resolvase; Belongs to the UPF0102 family.
 
  
 0.628
Dred_1087
CheC, inhibitor of MCP methylation; PFAM: surface presentation of antigens (SPOA) protein; CheC domain protein; KEGG: chy:CHY_1020 flagellar motor switch protein.
  
    0.617
Dred_2380
CheC, inhibitor of MCP methylation; TIGRFAM: flagellar motor switch protein FliN; PFAM: surface presentation of antigens (SPOA) protein; CheC domain protein; KEGG: chy:CHY_1020 flagellar motor switch protein.
  
    0.617
Dred_2145
KEGG: ava:Ava_4779 multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; Hpt domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein.
  
  
 0.608
Your Current Organism:
Desulfotomaculum reducens
NCBI taxonomy Id: 349161
Other names: D. reducens MI-1, Desulfotomaculum reducens MI-1, Desulfotomaculum reducens str. MI-1, Desulfotomaculum reducens strain MI-1
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