STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dred_2004PFAM: SpoVR family protein; KEGG: btl:BALH_0701 stage V sporulation protein R. (470 aa)    
Predicted Functional Partners:
Dred_2006
PFAM: PrkA serine kinase; PrkA AAA domain protein; KEGG: chy:CHY_1200 PrkA protein.
 
  
 0.996
Dred_2005
PFAM: protein of unknown function DUF444; KEGG: chy:CHY_1201 hypothetical protein; Belongs to the UPF0229 family.
 
  
 0.995
Dred_1250
PFAM: PhoH family protein; SMART: Nucleotide binding protein, PINc; KEGG: gsu:GSU1866 PhoH family protein.
  
    0.593
Dred_3092
Hypothetical protein.
   
    0.570
ku
DNA end-binding protein Ku; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.
       0.545
Dred_2002
PFAM: ATP dependent DNA ligase domain protein; ATP dependent DNA ligase; KEGG: mta:Moth_1488 ATP dependent DNA ligase, central.
       0.498
Dred_1163
Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
   
  
 0.471
smpB
SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]
      
 0.416
Dred_1095
PFAM: protein of unknown function DUF95, transmembrane; KEGG: swo:Swol_0605 uncharacterized membrane protein.
  
   
 0.406
Dred_2908
KEGG: mta:Moth_1391 spore coat peptide assembly protein cotJB.
   
  
 0.402
Your Current Organism:
Desulfotomaculum reducens
NCBI taxonomy Id: 349161
Other names: D. reducens MI-1, Desulfotomaculum reducens MI-1, Desulfotomaculum reducens str. MI-1, Desulfotomaculum reducens strain MI-1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.