STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dred_2013Replicative DNA helicase loader DnaI; SMART: AAA ATPase; KEGG: mta:Moth_1184 IstB-like ATP-binding protein. (283 aa)    
Predicted Functional Partners:
Dred_2103
TIGRFAM: primosome, DnaD subunit; PFAM: DnaD and phage-associated region; KEGG: chy:CHY_1235 DNA replication protein DnaD.
 
  
 0.781
Dred_2012
Hypothetical protein.
       0.773
Dred_3301
Primary replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily.
  
 
 0.707
Dred_2011
PFAM: t-RNA-binding domain protein; KEGG: cac:CAC2356 phenylalanyl-tRNA synthetase (beta subunit); Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
       0.682
Dred_0117
TIGRFAM: SpoIID/LytB domain; PFAM: Stage II sporulation D domain protein; KEGG: chy:CHY_0206 SpoIID/LytB domain protein.
   
    0.575
Dred_2014
Hypothetical protein.
       0.462
topB
DNA topoisomerase III; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA su [...]
  
  
 0.436
Dred_1918
KEGG: mta:Moth_1082 hypothetical protein.
  
     0.426
Dred_2377
KEGG: swo:Swol_1786 hypothetical protein.
  
     0.420
Your Current Organism:
Desulfotomaculum reducens
NCBI taxonomy Id: 349161
Other names: D. reducens MI-1, Desulfotomaculum reducens MI-1, Desulfotomaculum reducens str. MI-1, Desulfotomaculum reducens strain MI-1
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.