STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dred_2152Iron-only hydrogenase maturation protein HydF; TIGRFAM: small GTP-binding protein; PFAM: GTP-binding protein, HSR1-related; Miro domain protein; KEGG: mta:Moth_1277 small GTP-binding protein domain. (409 aa)    
Predicted Functional Partners:
Dred_2151
Iron-only hydrogenase maturation protein HydE; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: mta:Moth_1735 radical SAM.
   
 0.988
Dred_2150
Iron-only hydrogenase maturation protein HydG; PFAM: Radical SAM domain protein; biotin and thiamin synthesis associated; KEGG: mta:Moth_1734 biotin and thiamin synthesis associated.
  
 0.985
Dred_2153
KEGG: tte:TTE1595 hypothetical protein.
 
   
 0.951
Dred_1654
NAD(P)-dependent iron-only hydrogenase catalytic subunit; TIGRFAM: hydrogenases, Fe-only; PFAM: ferredoxin; 4Fe-4S ferredoxin, iron-sulfur binding domain protein; iron hydrogenase, small subunit; hydrogenase large subunit domain protein; KEGG: tte:TTE0894 NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G).
 
   
 0.839
Dred_2305
Ferredoxin 2; KEGG: tte:TTE0697 ferredoxin 2.
 
   
 0.827
gpsA
PFAM: NADP oxidoreductase, coenzyme F420-dependent; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; Ketopantoate reductase ApbA/PanE, N-terminal domain protein; KEGG: bsu:BG11366 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
  
  
 0.804
Dred_1651
NAD(P)-dependent iron-only hydrogenase catalytic subunit; TIGRFAM: hydrogenases, Fe-only; PFAM: ferredoxin; 4Fe-4S ferredoxin, iron-sulfur binding domain protein; iron hydrogenase, small subunit; hydrogenase large subunit domain protein; KEGG: mta:Moth_1717 iron hydrogenase, small subunit.
 
   
 0.804
Dred_3290
NAD(P)-dependent iron-only hydrogenase catalytic subunit; TIGRFAM: hydrogenases, Fe-only; PFAM: ferredoxin; 4Fe-4S ferredoxin, iron-sulfur binding domain protein; iron hydrogenase, small subunit; hydrogenase large subunit domain protein; KEGG: pca:Pcar_1605 NADH:ubiquinone oxidoreductase subunit.
 
   
 0.797
Dred_0074
Tyrosine lyase ThiH; TIGRFAM: thiazole biosynthesis protein ThiH; PFAM: Radical SAM domain protein; biotin and thiamin synthesis associated; KEGG: mta:Moth_1664 thiazole biosynthesis ThiH.
  
 0.788
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
   
  
 0.777
Your Current Organism:
Desulfotomaculum reducens
NCBI taxonomy Id: 349161
Other names: D. reducens MI-1, Desulfotomaculum reducens MI-1, Desulfotomaculum reducens str. MI-1, Desulfotomaculum reducens strain MI-1
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