STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dred_2189L-lactate transport; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family. (586 aa)    
Predicted Functional Partners:
Dred_0690
PFAM: protein of unknown function DUF162; protein of unknown function DUF224, cysteine-rich region domain protein; KEGG: ppd:Ppro_3135 protein of unknown function DUF224, cysteine-rich region domain protein.
 
  
 0.821
Dred_1257
PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase; ferredoxin-dependent glutamate synthase; KEGG: chy:CHY_0269 dehydrogenase, FMN-dependent family.
  
 0.787
Dred_0432
PFAM: protein of unknown function DUF162; KEGG: chy:CHY_0147 iron-sulfur cluster-binding protein.
 
  
 0.733
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
  
  
 0.732
Dred_2188
Transcriptional regulator, GntR family; PFAM: regulatory protein GntR, HTH; GntR domain protein; KEGG: dsy:DSY2275 hypothetical protein.
 
  
 0.718
fni
Isopentenyl-diphosphate delta-isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
  
  
 0.702
Dred_0433
CoB--CoM heterodisulfide reductase; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; protein of unknown function DUF162; protein of unknown function DUF224, cysteine-rich region domain protein; KEGG: mta:Moth_2305 hypothetical protein.
 
  
 0.689
Dred_0689
PFAM: protein of unknown function DUF162; KEGG: dsy:DSY1922 hypothetical protein.
 
  
 0.650
Dred_2187
Transcriptional regulator, GntR family; PFAM: regulatory protein GntR, HTH; GntR domain protein; KEGG: chy:CHY_0434 transcriptional regulator, GntR family.
  
 0.643
Dred_0369
PFAM: FAD linked oxidase domain protein; KEGG: tte:TTE0224 FAD/FMN-containing dehydrogenases.
 
  
 0.552
Your Current Organism:
Desulfotomaculum reducens
NCBI taxonomy Id: 349161
Other names: D. reducens MI-1, Desulfotomaculum reducens MI-1, Desulfotomaculum reducens str. MI-1, Desulfotomaculum reducens strain MI-1
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.