STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dred_2574PFAM: beta-lactamase domain protein; KEGG: cno:NT01CX_0354 metallo-beta-lactamase superfamily protein. (352 aa)    
Predicted Functional Partners:
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
      0.723
Dred_2575
KEGG: chy:CHY_2257 hypothetical protein.
       0.504
Dred_1029
TIGRFAM: type IV pilus assembly protein PilM; KEGG: sfu:Sfum_0537 type IV pilus assembly protein PilM.
  
   
 0.434
Dred_2907
Hypothetical protein.
   
    0.422
Dred_2573
PFAM: protein of unknown function DUF378; KEGG: btk:BT9727_4609 hypothetical protein.
       0.417
Dred_3143
PFAM: copper amine oxidase domain protein; KEGG: lwe:lwe0250 competence protein ComEC/Rec2-related protein.
 
  
0.406
cinA
TIGRFAM: competence/damage-inducible protein CinA; PFAM: molybdopterin binding domain; CinA domain protein; KEGG: dsy:DSY1955 hypothetical protein; Belongs to the CinA family.
      
 0.400
Your Current Organism:
Desulfotomaculum reducens
NCBI taxonomy Id: 349161
Other names: D. reducens MI-1, Desulfotomaculum reducens MI-1, Desulfotomaculum reducens str. MI-1, Desulfotomaculum reducens strain MI-1
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