STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dred_3262Two component transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein, AraC type; response regulator receiver; KEGG: cno:NT01CX_0496 two-component response regulator. (257 aa)    
Predicted Functional Partners:
Dred_2440
CheA signal transduction histidine kinase; PFAM: CheW domain protein; ATP-binding region, ATPase domain protein domain protein; Signal transducing histidine kinase, homodimeric; Hpt domain protein; P2 response regulator binding domain protein; KEGG: chy:CHY_0967 chemotaxis protein CheA.
  
 
 0.870
Dred_3263
Histidine kinase internal region; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase internal region; KEGG: cno:NT01CX_0495 sensor histidine kinase, putative.
  
 0.862
Dred_2381
PFAM: surface presentation of antigens (SPOA) protein; flagellar motor switch protein FliM; KEGG: chy:CHY_1019 flagellar motor switch protein FliM.
  
 
 0.836
Dred_2145
KEGG: ava:Ava_4779 multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; Hpt domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein.
 
 
 
0.758
Dred_1556
GAF sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: sth:STH843 two-component sensor histidine kinase.
 
 
 0.653
Dred_1293
PFAM: response regulator receiver; KEGG: sma:SAV6219 two-component system response regulator.
  
     0.651
Dred_2108
PFAM: regulatory protein, LuxR; response regulator receiver; KEGG: mta:Moth_0975 two component transcriptional regulator, LuxR family.
  
   
 0.580
Dred_1525
KEGG: swo:Swol_1054 signal transduction histidine kinase nitrogen specific-like protein; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold-3 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.
 
 
 
 0.560
Dred_0780
Diguanylate cyclase with PAS/PAC sensor; KEGG: dsy:DSY3403 HD-GYP domain protein; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; metal-dependent phosphohydrolase, HD sub domain; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; metal-dependent phosphohydrolase, HD region.
 
 
 
 0.555
Dred_1087
CheC, inhibitor of MCP methylation; PFAM: surface presentation of antigens (SPOA) protein; CheC domain protein; KEGG: chy:CHY_1020 flagellar motor switch protein.
  
 
 0.551
Your Current Organism:
Desulfotomaculum reducens
NCBI taxonomy Id: 349161
Other names: D. reducens MI-1, Desulfotomaculum reducens MI-1, Desulfotomaculum reducens str. MI-1, Desulfotomaculum reducens strain MI-1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.