Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Acry_0002Carboxylesterase; Serine hydrolase involved in the detoxification of formaldehyde. (283 aa)    
Predicted Functional Partners:
Acry_2794
PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
 0.999
gfa
S-(hydroxymethyl)glutathione synthase; Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione; Belongs to the Gfa family.
 
  
 0.942
Acry_0841
PFAM: NADH dehydrogenase (ubiquinone), 24 kDa subunit.
  
 
 0.915
Acry_0837
Formate dehydrogenase delta subunit.
    
  0.906
Acry_0839
TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: ferredoxin; 4Fe-4S ferredoxin, iron-sulfur binding domain protein; molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region.
    
  0.906
Acry_0840
PFAM: Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit.
    
  0.901
Acry_1127
PFAM: protein of unknown function DUF156.
  
  
 0.796
purU
Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).
  
  
 0.521
Acry_2668
Hypothetical protein.
     
 0.484
Acry_0995
PFAM: Sarcosine oxidase, gamma subunit.
   
    0.461
Your Current Organism:
Acidiphilium cryptum
NCBI taxonomy Id: 349163
Other names: A. cryptum JF-5, Acidiphilium cryptum JF-5, Acidiphilium cryptum str. JF-5, Acidiphilium cryptum strain JF-5, Acidiphilum cryptum JF-5
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