Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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Acry_0191Ketopantoate reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (305 aa)    
Predicted Functional Partners:
Acry_2462
TIGRFAM: 2-dehydropantoate 2-reductase; PFAM: NADP oxidoreductase, coenzyme F420-dependent; Ketopantoate reductase ApbA/PanE, N-terminal domain protein; Ketopantoate reductase ApbA/PanE, C-terminal domain protein.
  
  
 
0.929
panC
Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
    
 0.918
panB
Ketopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
    
 0.918
Acry_0190
PFAM: thioesterase superfamily protein.
       0.758
Acry_0189
Fructose PTS system EIIBC or EIIC component; TIGRFAM: PTS system, fructose-specific, IIB subunnit; PTS system, fructose subfamily, IIC subunit; PFAM: phosphotransferase system, EIIC; phosphotransferase system PTS, fructose-specific IIB subunit; 4.A.2.1.1; 4.A.2.1.1.
       0.645
Acry_0187
Phosphocarrier protein HPr / PTS system D-fructose-specific IIA component (F1P-forming), Frc family; TIGRFAM: phosphoenolpyruvate-protein phosphotransferase; PFAM: phosphocarrier HPr protein; PEP-utilizing enzyme; phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; PEP-utilising enzyme, mobile region; PEP-utilising enzyme domain protein; 4.A.2.1.1.
       0.583
Acry_0188
Fructose-1-phosphate kinase; PFAM: PfkB domain protein; Belongs to the carbohydrate kinase PfkB family.
       0.567
Your Current Organism:
Acidiphilium cryptum
NCBI taxonomy Id: 349163
Other names: A. cryptum JF-5, Acidiphilium cryptum JF-5, Acidiphilium cryptum str. JF-5, Acidiphilium cryptum strain JF-5, Acidiphilum cryptum JF-5
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