Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Acry_0334PFAM: hydrogenase-1 expression HyaE; Belongs to the HupG/HyaE family. (132 aa)    
Predicted Functional Partners:
Acry_0333
PFAM: HupH hydrogenase expression protein.
 
  
 0.996
Acry_0336
TIGRFAM: Ni/Fe-hydrogenase, b-type cytochrome subunit; PFAM: cytochrome B561.
 
  
 0.994
Acry_0335
Hydrogenase 1 maturation peptidase HyaD, Aspartic peptidase, MEROPS family A31; TIGRFAM: hydrogenase maturation protease; hydrogenase expression/formation protein; PFAM: peptidase M52, hydrogen uptake protein.
 
  
 0.977
Acry_0337
PFAM: nickel-dependent hydrogenase, large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
 
 0.963
Acry_0338
TIGRFAM: hydrogenase (NiFe) small subunit HydA; PFAM: NADH ubiquinone oxidoreductase, 20 kDa subunit; Nickel-iron dehydrogenase small subunit, N-terminal domain protein.
 
 
 0.963
Acry_0332
PFAM: Rubredoxin-type Fe(Cys)4 protein.
 
  
 0.953
hypA
Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
   
 0.917
Acry_0330
TIGRFAM: hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein, P47K.
 
  
 0.871
Acry_0339
PFAM: protein of unknown function DUF1486.
       0.458
Acry_0340
PFAM: cyclase/dehydrase.
       0.452
Your Current Organism:
Acidiphilium cryptum
NCBI taxonomy Id: 349163
Other names: A. cryptum JF-5, Acidiphilium cryptum JF-5, Acidiphilium cryptum str. JF-5, Acidiphilium cryptum strain JF-5, Acidiphilum cryptum JF-5
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