Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
xylBTIGRFAM: xylulokinase; PFAM: carbohydrate kinase, FGGY. (496 aa)    
Predicted Functional Partners:
Acry_0022
PFAM: ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.
    
 0.915
Acry_0827
PFAM: ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.
    
 0.915
Acry_0501
Transcriptional regulator, LacI family; PFAM: regulatory protein, LacI; periplasmic binding protein/LacI transcriptional regulator.
 
 
 
 0.676
tal
Glucose-6-phosphate isomerase / transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the GPI family.
  
 
 0.579
Acry_1220
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 
 0.570
Acry_0717
PFAM: Transketolase domain protein.
    
 0.521
Acry_0718
Transketolase subunit B; PFAM: Transketolase, central region; Transketolase domain protein.
    
 0.509
Acry_2013
Pyruvate dehydrogenase (acetyl-transferring); Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
     
  0.500
Acry_2065
Transketolase, central region; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
     
  0.500
Acry_2319
PFAM: Xylose isomerase domain protein TIM barrel.
     
  0.500
Your Current Organism:
Acidiphilium cryptum
NCBI taxonomy Id: 349163
Other names: A. cryptum JF-5, Acidiphilium cryptum JF-5, Acidiphilium cryptum str. JF-5, Acidiphilium cryptum strain JF-5, Acidiphilum cryptum JF-5
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