Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Acry_0545PFAM: aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (458 aa)    
Predicted Functional Partners:
Acry_2180
PFAM: Orn/DAP/Arg decarboxylase 2; Belongs to the Orn/Lys/Arg decarboxylase class-II family.
  
  
 0.918
Acry_1254
PFAM: aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
    
 0.902
Acry_2390
PFAM: aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
    
 0.902
speE
Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine; Belongs to the spermidine/spermine synthase family.
    
  0.900
Acry_0546
Glutamate--putrescine ligase; PFAM: glutamine synthetase, catalytic region.
   
 0.892
Acry_0538
Glutamate--putrescine ligase; PFAM: glutamine synthetase, catalytic region.
   
 0.808
Acry_0537
Gamma-glutamylputrescine oxidase; PFAM: FAD dependent oxidoreductase.
 
  
 0.799
bioD
Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.
 
  
 0.796
bioB
Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.
  
  
 0.777
Acry_0544
Putative transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; Cupin 2, conserved barrel domain protein.
 
   
 0.674
Your Current Organism:
Acidiphilium cryptum
NCBI taxonomy Id: 349163
Other names: A. cryptum JF-5, Acidiphilium cryptum JF-5, Acidiphilium cryptum str. JF-5, Acidiphilium cryptum strain JF-5, Acidiphilum cryptum JF-5
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