Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Acry_0635Hypothetical protein. (419 aa)    
Predicted Functional Partners:
Acry_1400
PFAM: NADH-ubiquinone oxidoreductase, chain 49kDa.
 
 
 0.981
Acry_0606
PFAM: NADH-ubiquinone oxidoreductase, chain 49kDa.
 
 
 0.969
Acry_0637
Ni Fe-hydrogenase III large subunit-like protein.
 
 
 0.961
Acry_0607
PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; NADH ubiquinone oxidoreductase, 20 kDa subunit.
 
 
 0.920
Acry_0638
PFAM: NADH ubiquinone oxidoreductase, 20 kDa subunit.
 
 
 0.908
Acry_0636
Hypothetical protein.
  
 
 0.867
Acry_1399
NADH dehydrogenase (quinone); PFAM: NADH/Ubiquinone/plastoquinone (complex I).
 
  
 0.842
nuoC-2
NADH dehydrogenase subunit C / NADH dehydrogenase subunit D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family.
  
 
 0.806
Acry_0605
NADH dehydrogenase (quinone); PFAM: NADH/Ubiquinone/plastoquinone (complex I).
 
  
 0.803
rnhB
RNase HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
       0.779
Your Current Organism:
Acidiphilium cryptum
NCBI taxonomy Id: 349163
Other names: A. cryptum JF-5, Acidiphilium cryptum JF-5, Acidiphilium cryptum str. JF-5, Acidiphilium cryptum strain JF-5, Acidiphilum cryptum JF-5
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