Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Acry_0847Gamma-glutamyl-gamma-aminobutyrate hydrolase; PFAM: glutamine amidotransferase class-I; peptidase C26. (246 aa)    
Predicted Functional Partners:
Acry_0844
TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase, middle domain protein; Belongs to the folylpolyglutamate synthase family.
  
  
 0.727
accD
acetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.
   
   0.718
Acry_0848
TIGRFAM: drug resistance transporter, Bcr/CflA subfamily; PFAM: major facilitator superfamily MFS_1.
       0.716
Acry_0846
Hypothetical protein.
       0.709
Acry_0537
Gamma-glutamylputrescine oxidase; PFAM: FAD dependent oxidoreductase.
 
  
 0.697
Acry_0538
Glutamate--putrescine ligase; PFAM: glutamine synthetase, catalytic region.
 
  
 0.594
Acry_2393
PFAM: glutamine synthetase, catalytic region.
 
  
 0.510
Acry_0842
Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family.
       0.506
Acry_0843
PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein.
       0.506
Acry_0546
Glutamate--putrescine ligase; PFAM: glutamine synthetase, catalytic region.
 
  
 0.488
Your Current Organism:
Acidiphilium cryptum
NCBI taxonomy Id: 349163
Other names: A. cryptum JF-5, Acidiphilium cryptum JF-5, Acidiphilium cryptum str. JF-5, Acidiphilium cryptum strain JF-5, Acidiphilum cryptum JF-5
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