Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Acry_0868PFAM: protein of unknown function DUF461. (144 aa)    
Predicted Functional Partners:
Acry_2945
Cytochrome b/b6, N-terminal domain protein; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
  
 
 0.830
Acry_1096
PFAM: cytochrome c oxidase, subunit II.
  
 
 0.774
Acry_2167
Cytochrome c oxidase, subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
  
 
 0.761
Acry_3043
Monoheme cytochrome SoxX (sulfur oxidation); PFAM: cytochrome c, class I.
  
 
 0.749
Acry_0043
Gluconate 2-dehydrogenase (acceptor); PFAM: cytochrome c, class I.
  
 
 0.747
Acry_1094
Cytochrome bo3 quinol oxidase subunit 3.
  
   0.737
Acry_2164
PFAM: cytochrome c oxidase, subunit III.
  
   0.737
Acry_1563
Cytochrome c-like protein.
   
 
 0.708
Acry_1095
Cytochrome bo3 quinol oxidase subunit 1 apoprotein; PFAM: cytochrome c oxidase, subunit I; Belongs to the heme-copper respiratory oxidase family.
  
   0.672
Acry_2166
Cytochrome-c oxidase; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
  
   0.672
Your Current Organism:
Acidiphilium cryptum
NCBI taxonomy Id: 349163
Other names: A. cryptum JF-5, Acidiphilium cryptum JF-5, Acidiphilium cryptum str. JF-5, Acidiphilium cryptum strain JF-5, Acidiphilum cryptum JF-5
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