STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Acry_1069Hypothetical protein. (279 aa)    
Predicted Functional Partners:
Acry_1067
Ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit; PFAM: ribulose bisphosphate carboxylase, large chain; Belongs to the RuBisCO large chain family.
 
  
 0.950
Acry_1068
PFAM: type III effector Hrp-dependent outers.
 
     0.947
Acry_1070
Monosaccharide ABC transporter substrate-binding protein, CUT2 family; 3.A.1.2.-.
 
     0.835
Acry_2832
TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein.
  
  
 0.805
leuD
3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.
  
  
 0.804
leuC
3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
  
  
 0.804
Acry_1066
Transcriptional regulator, GntR family; PFAM: regulatory protein GntR, HTH; GntR domain protein.
 
     0.775
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
  
  
 0.761
Acry_2695
hydroxymethylglutaryl-CoA lyase; PFAM: pyruvate carboxyltransferase.
  
  
 0.761
Acry_1666
PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase.
  
  
 0.701
Your Current Organism:
Acidiphilium cryptum
NCBI taxonomy Id: 349163
Other names: A. cryptum JF-5, Acidiphilium cryptum JF-5, Acidiphilium cryptum str. JF-5, Acidiphilium cryptum strain JF-5, Acidiphilum cryptum JF-5
Server load: low (30%) [HD]