node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Acry_0413 | Acry_1700 | Acry_0413 | Acry_1700 | Hypothetical protein. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.519 |
Acry_0413 | ahcY | Acry_0413 | Acry_1228 | Hypothetical protein. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.920 |
Acry_0413 | metK | Acry_0413 | Acry_1054 | Hypothetical protein. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.420 |
Acry_1298 | Acry_1700 | Acry_1298 | Acry_1700 | PFAM: homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase, NAD-binding. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.938 |
Acry_1298 | Acry_2103 | Acry_1298 | Acry_2103 | PFAM: homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase, NAD-binding. | TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes. | 0.866 |
Acry_1298 | Acry_2264 | Acry_1298 | Acry_2264 | PFAM: homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase, NAD-binding. | TIGRFAM: cystathionine beta-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes. | 0.862 |
Acry_1298 | ahcY | Acry_1298 | Acry_1228 | PFAM: homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase, NAD-binding. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.820 |
Acry_1298 | metE | Acry_1298 | Acry_2208 | PFAM: homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase, NAD-binding. | Methionine synthase (B12-independent); Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.880 |
Acry_1298 | metZ | Acry_1298 | Acry_3103 | PFAM: homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase, NAD-binding. | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.862 |
Acry_1489 | Acry_1700 | Acry_1489 | Acry_1700 | PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.893 |
Acry_1489 | Acry_2103 | Acry_1489 | Acry_2103 | PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit. | TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes. | 0.857 |
Acry_1489 | Acry_2264 | Acry_1489 | Acry_2264 | PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit. | TIGRFAM: cystathionine beta-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes. | 0.960 |
Acry_1489 | Acry_2560 | Acry_1489 | Acry_2560 | PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit. | TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.915 |
Acry_1489 | ahcY | Acry_1489 | Acry_1228 | PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.849 |
Acry_1489 | metE | Acry_1489 | Acry_2208 | PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit. | Methionine synthase (B12-independent); Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.824 |
Acry_1489 | metZ | Acry_1489 | Acry_3103 | PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit. | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.959 |
Acry_1700 | Acry_0413 | Acry_1700 | Acry_0413 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Hypothetical protein. | 0.519 |
Acry_1700 | Acry_1298 | Acry_1700 | Acry_1298 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | PFAM: homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase, NAD-binding. | 0.938 |
Acry_1700 | Acry_1489 | Acry_1700 | Acry_1489 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit. | 0.893 |
Acry_1700 | Acry_2103 | Acry_1700 | Acry_2103 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes. | 0.957 |