Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Acry_1256PFAM: AMP-dependent synthetase and ligase. (572 aa)    
Predicted Functional Partners:
Acry_0662
PFAM: AMP-dependent synthetase and ligase.
  
  
 
0.921
Acry_0254
PFAM: AMP-dependent synthetase and ligase.
  
  
 
0.920
Acry_1260
PFAM: acyl-CoA dehydrogenase domain protein.
 
 
  0.899
Acry_1255
Hypothetical protein.
 
   
 0.803
Acry_1257
3-ketoacyl-CoA thiolase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.784
Acry_1259
PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; dTDP-4-dehydrorhamnose reductase; KR; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
   0.762
Acry_1258
PFAM: MaoC domain protein dehydratase.
       0.752
Acry_1261
Xylene monooxygenase electron transfer component; PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein.
     
 0.662
Acry_1262
Alkane 1-monooxygenase; PFAM: fatty acid desaturase.
     
 0.661
Acry_0007
PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain.
 
 
  0.580
Your Current Organism:
Acidiphilium cryptum
NCBI taxonomy Id: 349163
Other names: A. cryptum JF-5, Acidiphilium cryptum JF-5, Acidiphilium cryptum str. JF-5, Acidiphilium cryptum strain JF-5, Acidiphilum cryptum JF-5
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