Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Acry_2285PFAM: HpcH/HpaI aldolase; Belongs to the HpcH/HpaI aldolase family. (251 aa)    
Predicted Functional Partners:
Acry_2327
PFAM: HpcH/HpaI aldolase; Belongs to the HpcH/HpaI aldolase family.
  
  
 
0.906
Acry_0274
TIGRFAM: succinic semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 
 0.905
Acry_1965
Succinate semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase.
  
 
 0.905
Acry_2286
Pyroglutamyl-peptidase I, Cysteine peptidase, MEROPS family C15; Removes 5-oxoproline from various penultimate amino acid residues except L-proline.
       0.553
Acry_1443
PFAM: Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B.
  
  
 0.404
Your Current Organism:
Acidiphilium cryptum
NCBI taxonomy Id: 349163
Other names: A. cryptum JF-5, Acidiphilium cryptum JF-5, Acidiphilium cryptum str. JF-5, Acidiphilium cryptum strain JF-5, Acidiphilum cryptum JF-5
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