close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mthe_0010PFAM: molybdopterin biosynthesis MoaE; KEGG: tko:TK2115 molybdopterin converting factor, subunit 2. (131 aa)    
Predicted Functional Partners:
Mthe_0009
Molybdopterin synthase subunit MoaD; TIGRFAM: MoaD family protein; PFAM: thiamineS protein; KEGG: afu:AF1624 molybdopterin converting factor, subunit 1.
  
 0.999
moaC
GTP cyclohydrolase subunit MoaC; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.
 
 
 0.999
Mthe_0306
TIGRFAM: molybdenum cofactor synthesis domain; PFAM: molybdopterin binding domain; KEGG: mac:MA0187 molybdenum cofactor biosynthesis protein B.
 
 
 0.985
Mthe_0544
PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: mac:MA0255 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate synthesis protein ThiF.
 
 0.973
Mthe_0160
Molybdopterin molybdochelatase; TIGRFAM: molybdenum cofactor synthesis domain; PFAM: molybdopterin binding domain; MoeA domain protein, domain I and II; MoeA domain protein, domain IV; KEGG: mba:Mbar_A0575 molybdenum cofactor biosynthesis protein.
 
 
 0.906
moaA
GTP cyclohydrolase subunit MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family.
 
  
 0.904
Mthe_0386
Molybdopterin molybdochelatase; TIGRFAM: molybdenum cofactor synthesis domain; PFAM: molybdopterin binding domain; MoeA domain protein, domain I and II; MoeA domain protein, domain IV; KEGG: mac:MA4087 molybdenum cofactor biosynthesis protein MoeA2.
 
  
 0.827
Mthe_0326
TIGRFAM: molybdopterin-guanine dinucleotide biosynthesis protein B; PFAM: molybdopterin-guanine dinucleotide biosynthesis MobB region; KEGG: mac:MA1978 molybdopterin-guanine dinucleotide biosynthesis protein B/molybdopterin converting factor, large subunit.
  
 
 0.823
Mthe_0011
PFAM: CutA1 divalent ion tolerance protein; KEGG: ape:APE1668 106aa long hypothetical periplasmic divalent cation tolerance protein.
       0.780
Mthe_0499
KEGG: mma:MM0912 hypothetical protein; Belongs to the UPF0288 family.
   
    0.763
Your Current Organism:
Methanothrix thermoacetophila
NCBI taxonomy Id: 349307
Other names: M. thermoacetophila PT, Methanosaeta thermophila PT, Methanothrix thermoacetophila PT, Methanothrix thermophila DSM 6194, Methanothrix thermophila PT
Server load: medium (48%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.