node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Mthe_0846 | cofC | Mthe_0846 | Mthe_0159 | PFAM: amino acid-binding ACT domain protein; KEGG: mba:Mbar_A1897 hypothetical protein. | Phospholactate guanylyltransferase; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family. | 0.656 |
Mthe_1428 | cofC | Mthe_1428 | Mthe_0159 | TIGRFAM: NADPH-dependent F420 reductase; PFAM: NADP oxidoreductase, coenzyme F420-dependent; KEGG: mhu:Mhun_3174 NADPH-dependent F420 reductase. | Phospholactate guanylyltransferase; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family. | 0.747 |
Mthe_1428 | cofD | Mthe_1428 | Mthe_1438 | TIGRFAM: NADPH-dependent F420 reductase; PFAM: NADP oxidoreductase, coenzyme F420-dependent; KEGG: mhu:Mhun_3174 NADPH-dependent F420 reductase. | LPPG:FO 2-phospho-L-lactate transferase; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP. | 0.834 |
Mthe_1428 | cofE | Mthe_1428 | Mthe_0158 | TIGRFAM: NADPH-dependent F420 reductase; PFAM: NADP oxidoreductase, coenzyme F420-dependent; KEGG: mhu:Mhun_3174 NADPH-dependent F420 reductase. | Coenzyme F420-0 gamma-glutamyl ligase; Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8- didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420- 0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives. | 0.769 |
Mthe_1428 | cofG | Mthe_1428 | Mthe_0221 | TIGRFAM: NADPH-dependent F420 reductase; PFAM: NADP oxidoreductase, coenzyme F420-dependent; KEGG: mhu:Mhun_3174 NADPH-dependent F420 reductase. | FO synthase subunit 1; Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8- hydroxy-5-deazariboflavin from 5-amino-5-(4-hydroxybenzyl)-6-(D- ribitylimino)-5,6-dihydrouracil. | 0.766 |
Mthe_1428 | cofH | Mthe_1428 | Mthe_0284 | TIGRFAM: NADPH-dependent F420 reductase; PFAM: NADP oxidoreductase, coenzyme F420-dependent; KEGG: mhu:Mhun_3174 NADPH-dependent F420 reductase. | FO synthase subunit 2; Catalyzes the radical-mediated synthesis of 5-amino-5-(4- hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil from 5-amino-6-(D- ribitylamino)uracil and L-tyrosine. | 0.585 |
Mthe_1428 | mer | Mthe_1428 | Mthe_0205 | TIGRFAM: NADPH-dependent F420 reductase; PFAM: NADP oxidoreductase, coenzyme F420-dependent; KEGG: mhu:Mhun_3174 NADPH-dependent F420 reductase. | Methylenetetrahydromethanopterin reductase; Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT; Belongs to the mer family. | 0.813 |
Mthe_1623 | Mthe_1624 | Mthe_1623 | Mthe_1624 | KEGG: mbu:Mbur_1458 sulfopyruvate decarboxylase. | Sulfopyruvate decarboxylase subunit beta; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; KEGG: mbu:Mbur_1459 thiamine pyrophosphate enzyme-like TPP-binding. | 0.999 |
Mthe_1623 | cofC | Mthe_1623 | Mthe_0159 | KEGG: mbu:Mbur_1458 sulfopyruvate decarboxylase. | Phospholactate guanylyltransferase; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family. | 0.825 |
Mthe_1623 | cofG | Mthe_1623 | Mthe_0221 | KEGG: mbu:Mbur_1458 sulfopyruvate decarboxylase. | FO synthase subunit 1; Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8- hydroxy-5-deazariboflavin from 5-amino-5-(4-hydroxybenzyl)-6-(D- ribitylimino)-5,6-dihydrouracil. | 0.804 |
Mthe_1623 | cofH | Mthe_1623 | Mthe_0284 | KEGG: mbu:Mbur_1458 sulfopyruvate decarboxylase. | FO synthase subunit 2; Catalyzes the radical-mediated synthesis of 5-amino-5-(4- hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil from 5-amino-6-(D- ribitylamino)uracil and L-tyrosine. | 0.806 |
Mthe_1623 | mfnB | Mthe_1623 | Mthe_0348 | KEGG: mbu:Mbur_1458 sulfopyruvate decarboxylase. | Protein of unknown function DUF556; Catalyzes the formation of 4-(hydroxymethyl)-2- furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P). | 0.801 |
Mthe_1624 | Mthe_1623 | Mthe_1624 | Mthe_1623 | Sulfopyruvate decarboxylase subunit beta; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; KEGG: mbu:Mbur_1459 thiamine pyrophosphate enzyme-like TPP-binding. | KEGG: mbu:Mbur_1458 sulfopyruvate decarboxylase. | 0.999 |
Mthe_1624 | cofC | Mthe_1624 | Mthe_0159 | Sulfopyruvate decarboxylase subunit beta; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; KEGG: mbu:Mbur_1459 thiamine pyrophosphate enzyme-like TPP-binding. | Phospholactate guanylyltransferase; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family. | 0.824 |
Mthe_1624 | cofG | Mthe_1624 | Mthe_0221 | Sulfopyruvate decarboxylase subunit beta; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; KEGG: mbu:Mbur_1459 thiamine pyrophosphate enzyme-like TPP-binding. | FO synthase subunit 1; Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8- hydroxy-5-deazariboflavin from 5-amino-5-(4-hydroxybenzyl)-6-(D- ribitylimino)-5,6-dihydrouracil. | 0.804 |
Mthe_1624 | cofH | Mthe_1624 | Mthe_0284 | Sulfopyruvate decarboxylase subunit beta; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; KEGG: mbu:Mbur_1459 thiamine pyrophosphate enzyme-like TPP-binding. | FO synthase subunit 2; Catalyzes the radical-mediated synthesis of 5-amino-5-(4- hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil from 5-amino-6-(D- ribitylamino)uracil and L-tyrosine. | 0.806 |
Mthe_1624 | mfnB | Mthe_1624 | Mthe_0348 | Sulfopyruvate decarboxylase subunit beta; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; KEGG: mbu:Mbur_1459 thiamine pyrophosphate enzyme-like TPP-binding. | Protein of unknown function DUF556; Catalyzes the formation of 4-(hydroxymethyl)-2- furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P). | 0.801 |
cofC | Mthe_0846 | Mthe_0159 | Mthe_0846 | Phospholactate guanylyltransferase; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family. | PFAM: amino acid-binding ACT domain protein; KEGG: mba:Mbar_A1897 hypothetical protein. | 0.656 |
cofC | Mthe_1428 | Mthe_0159 | Mthe_1428 | Phospholactate guanylyltransferase; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family. | TIGRFAM: NADPH-dependent F420 reductase; PFAM: NADP oxidoreductase, coenzyme F420-dependent; KEGG: mhu:Mhun_3174 NADPH-dependent F420 reductase. | 0.747 |
cofC | Mthe_1623 | Mthe_0159 | Mthe_1623 | Phospholactate guanylyltransferase; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family. | KEGG: mbu:Mbur_1458 sulfopyruvate decarboxylase. | 0.825 |