Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Mthe_0366PFAM: translation initiation factor SUI1; KEGG: mba:Mbar_A0534 translation initiation factor SUI1; Belongs to the SUI1 family. (102 aa)    
Predicted Functional Partners:
rps3
SSU ribosomal protein S3P; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family.
  
 
 0.974
rps17
SSU ribosomal protein S17P; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
  
 
 0.967
rps19
SSU ribosomal protein S19P; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
  
 
 0.955
rps4e
SSU ribosomal protein S4E; PFAM: RNA-binding S4 domain protein; KOW domain protein; Ribosomal protein S4E-like; Ribosomal protein S4E, central; KEGG: mma:MM2136 SSU ribosomal protein S4E; Belongs to the eukaryotic ribosomal protein eS4 family.
  
 
 0.954
rps5
SSU ribosomal protein S5P; With S4 and S12 plays an important role in translational accuracy.
  
 
 0.946
rps14
SSU ribosomal protein S14P; Binds 16S rRNA, required for the assembly of 30S particles.
  
   0.945
rps8
SSU ribosomal protein S8P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.
  
 
 0.942
rnp1
Ribonuclease P protein subunit Rpp29; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 1 family.
  
  
 0.940
rps17e
KEGG: pfu:PF1491 30S ribosomal protein S17e; Belongs to the eukaryotic ribosomal protein eS17 family.
 
   0.934
eif1a
Translation initiation factor 1A (aeIF-1A); Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.
 
 
 0.929
Your Current Organism:
Methanothrix thermoacetophila
NCBI taxonomy Id: 349307
Other names: M. thermoacetophila PT, Methanosaeta thermophila PT, Methanothrix thermoacetophila PT, Methanothrix thermophila DSM 6194, Methanothrix thermophila PT
Server load: low (34%) [HD]