STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mthe_0421PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: mbu:Mbur_0211 nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase. (245 aa)    
Predicted Functional Partners:
priS
DNA primase small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. [...]
       0.737
Mthe_1517
Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: noc:Noc_2450 PAS sensor signal transduction histidine kinase.
  
 
 0.724
Mthe_1524
Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: noc:Noc_2450 PAS sensor signal transduction histidine kinase.
  
 
 0.724
Mthe_0413
PFAM: peptidase U62, modulator of DNA gyrase; KEGG: mbu:Mbur_0882 peptidase U62, modulator of DNA gyrase.
  
    0.663
Mthe_0416
PFAM: RNA binding S1 domain protein; Eukaryotic translation initiation factor 2, alpha subunit; KEGG: mbu:Mbur_1396 translation initiation factor 2, alpha subunit.
 
     0.661
Mthe_0414
PFAM: protein of unknown function DUF75; KEGG: afu:AF0525 hypothetical protein.
       0.615
nop10
Nucleolar RNA-binding protein Nop10p; Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA.
       0.615
rps27e
PFAM: Ribosomal protein S27E; KEGG: mma:MM1808 SSU ribosomal protein S27E.
       0.615
rpl44e
LSU ribosomal protein L44E; Binds to the 23S rRNA.
       0.615
Mthe_0419
KEGG: mbu:Mbur_1393 hypothetical protein.
       0.615
Your Current Organism:
Methanothrix thermoacetophila
NCBI taxonomy Id: 349307
Other names: M. thermoacetophila PT, Methanosaeta thermophila PT, Methanothrix thermoacetophila PT, Methanothrix thermophila DSM 6194, Methanothrix thermophila PT
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