STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mthe_0557MRP/NBP35 family ATP-binding protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (281 aa)    
Predicted Functional Partners:
Mthe_1052
F420H2 dehydrogenase subunit C; PFAM: NADH-ubiquinone oxidoreductase, chain 49kDa; KEGG: mac:MA1498 F(420)H(2) dehydrogenase, subunit FpoD.
    
 0.724
Mthe_1051
KEGG: mma:MM2490 F420H2 dehydrogenase subunit; TIGRFAM: NADH-quinone oxidoreductase, B subunit; PFAM: NADH ubiquinone oxidoreductase, 20 kDa subunit; Belongs to the complex I 20 kDa subunit family.
  
 
 0.687
Mthe_1054
PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: mba:Mbar_A3407 F(420)H(2) dehydrogenase, subunit FpoI.
  
 
 0.656
Mthe_1337
KEGG: mta:Moth_2185 4Fe-4S ferredoxin, iron-sulfur binding.
  
 
 0.656
Mthe_0556
PFAM: protein of unknown function DUF134; KEGG: mac:MA4245 hypothetical protein.
  
    0.574
Mthe_0559
PFAM: Dinitrogenase iron-molybdenum cofactor biosynthesis; KEGG: mbu:Mbur_0620 dinitrogenase iron-molybdenum cofactor biosynthesis.
 
  
 0.493
Mthe_0250
PFAM: low molecular weight phosphotyrosine protein phosphatase; KEGG: mma:MM0574 arsenate reductase.
  
 
 0.472
Mthe_0373
MiaB-like tRNA modifying enzyme; KEGG: pab:PAB1134 hypothetical protein; TIGRFAM: RNA modification enzyme, MiaB family; MiaB-like tRNA modifying enzyme; PFAM: deoxyribonuclease/rho motif-related TRAM; Radical SAM domain protein; Protein of unknown function UPF0004-like; SMART: Elongator protein 3/MiaB/NifB.
 
  
 0.469
Mthe_0560
PFAM: Dinitrogenase iron-molybdenum cofactor biosynthesis; KEGG: mbu:Mbur_0621 dinitrogenase iron-molybdenum cofactor biosynthesis.
 
  
 0.466
iscS
Aminotransferase, class V; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
 
  
 0.460
Your Current Organism:
Methanothrix thermoacetophila
NCBI taxonomy Id: 349307
Other names: M. thermoacetophila PT, Methanosaeta thermophila PT, Methanothrix thermoacetophila PT, Methanothrix thermophila DSM 6194, Methanothrix thermophila PT
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