| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Mthe_0803 | Mthe_1416 | Mthe_0803 | Mthe_1416 | TIGRFAM: DJ-1 family protein; PFAM: ThiJ/PfpI domain protein; KEGG: det:DET0118 DJ-1 family protein. | 1-Cys peroxiredoxin / 3-Cys thioredoxin peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. | 0.717 |
| Mthe_0803 | dnaJ | Mthe_0803 | Mthe_0730 | TIGRFAM: DJ-1 family protein; PFAM: ThiJ/PfpI domain protein; KEGG: det:DET0118 DJ-1 family protein. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.716 |
| Mthe_0803 | dnaK | Mthe_0803 | Mthe_0731 | TIGRFAM: DJ-1 family protein; PFAM: ThiJ/PfpI domain protein; KEGG: det:DET0118 DJ-1 family protein. | Chaperone protein DnaK; Acts as a chaperone. | 0.719 |
| Mthe_0803 | rpl13 | Mthe_0803 | Mthe_0482 | TIGRFAM: DJ-1 family protein; PFAM: ThiJ/PfpI domain protein; KEGG: det:DET0118 DJ-1 family protein. | LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.653 |
| Mthe_0803 | rpl14 | Mthe_0803 | Mthe_1718 | TIGRFAM: DJ-1 family protein; PFAM: ThiJ/PfpI domain protein; KEGG: det:DET0118 DJ-1 family protein. | LSU ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. | 0.667 |
| Mthe_0803 | rpl5 | Mthe_0803 | Mthe_1715 | TIGRFAM: DJ-1 family protein; PFAM: ThiJ/PfpI domain protein; KEGG: det:DET0118 DJ-1 family protein. | LSU ribosomal protein L5P; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. | 0.688 |
| Mthe_0803 | rps10 | Mthe_0803 | Mthe_0822 | TIGRFAM: DJ-1 family protein; PFAM: ThiJ/PfpI domain protein; KEGG: det:DET0118 DJ-1 family protein. | SSU ribosomal protein S10P; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. | 0.707 |
| Mthe_0803 | rps19 | Mthe_0803 | Mthe_1724 | TIGRFAM: DJ-1 family protein; PFAM: ThiJ/PfpI domain protein; KEGG: det:DET0118 DJ-1 family protein. | SSU ribosomal protein S19P; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. | 0.676 |
| Mthe_0803 | rps2 | Mthe_0803 | Mthe_0478 | TIGRFAM: DJ-1 family protein; PFAM: ThiJ/PfpI domain protein; KEGG: det:DET0118 DJ-1 family protein. | PFAM: ribosomal protein S2; KEGG: mbu:Mbur_2393 ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. | 0.630 |
| Mthe_0803 | rps3 | Mthe_0803 | Mthe_1722 | TIGRFAM: DJ-1 family protein; PFAM: ThiJ/PfpI domain protein; KEGG: det:DET0118 DJ-1 family protein. | SSU ribosomal protein S3P; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family. | 0.664 |
| Mthe_1416 | Mthe_0803 | Mthe_1416 | Mthe_0803 | 1-Cys peroxiredoxin / 3-Cys thioredoxin peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. | TIGRFAM: DJ-1 family protein; PFAM: ThiJ/PfpI domain protein; KEGG: det:DET0118 DJ-1 family protein. | 0.717 |
| Mthe_1416 | dnaK | Mthe_1416 | Mthe_0731 | 1-Cys peroxiredoxin / 3-Cys thioredoxin peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. | Chaperone protein DnaK; Acts as a chaperone. | 0.818 |
| Mthe_1416 | rps2 | Mthe_1416 | Mthe_0478 | 1-Cys peroxiredoxin / 3-Cys thioredoxin peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. | PFAM: ribosomal protein S2; KEGG: mbu:Mbur_2393 ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. | 0.452 |
| dnaJ | Mthe_0803 | Mthe_0730 | Mthe_0803 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | TIGRFAM: DJ-1 family protein; PFAM: ThiJ/PfpI domain protein; KEGG: det:DET0118 DJ-1 family protein. | 0.716 |
| dnaJ | dnaK | Mthe_0730 | Mthe_0731 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Chaperone protein DnaK; Acts as a chaperone. | 0.999 |
| dnaJ | rpl13 | Mthe_0730 | Mthe_0482 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.878 |
| dnaJ | rpl14 | Mthe_0730 | Mthe_1718 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | LSU ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. | 0.891 |
| dnaJ | rpl5 | Mthe_0730 | Mthe_1715 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | LSU ribosomal protein L5P; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. | 0.761 |
| dnaJ | rps10 | Mthe_0730 | Mthe_0822 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | SSU ribosomal protein S10P; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. | 0.783 |
| dnaJ | rps2 | Mthe_0730 | Mthe_0478 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | PFAM: ribosomal protein S2; KEGG: mbu:Mbur_2393 ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. | 0.775 |
STRING v12.5 is now available!
