node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Mthe_0311 | Mthe_1218 | Mthe_0311 | Mthe_1218 | Conserved hypothetical protein; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Belongs to the adenylate kinase family. AK6 subfamily. | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: mac:MA3971 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.900 |
Mthe_0311 | adk | Mthe_0311 | Mthe_1504 | Conserved hypothetical protein; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Belongs to the adenylate kinase family. AK6 subfamily. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.936 |
Mthe_0311 | hpt | Mthe_0311 | Mthe_1111 | Conserved hypothetical protein; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Belongs to the adenylate kinase family. AK6 subfamily. | Phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily. | 0.908 |
Mthe_0311 | surE | Mthe_0311 | Mthe_1272 | Conserved hypothetical protein; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Belongs to the adenylate kinase family. AK6 subfamily. | 3'-nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.900 |
Mthe_1099 | Mthe_1218 | Mthe_1099 | Mthe_1218 | PFAM: Protein of unknown function DUF1297; Protein of unknown function DUF1246; KEGG: mac:MA3689 hypothetical protein. | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: mac:MA3971 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.939 |
Mthe_1099 | Mthe_1511 | Mthe_1099 | Mthe_1511 | PFAM: Protein of unknown function DUF1297; Protein of unknown function DUF1246; KEGG: mac:MA3689 hypothetical protein. | PFAM: AICARFT/IMPCHase bienzyme, formylation region; KEGG: mca:MCA1747 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase. | 0.908 |
Mthe_1099 | hpt | Mthe_1099 | Mthe_1111 | PFAM: Protein of unknown function DUF1297; Protein of unknown function DUF1246; KEGG: mac:MA3689 hypothetical protein. | Phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily. | 0.902 |
Mthe_1099 | purP | Mthe_1099 | Mthe_0184 | PFAM: Protein of unknown function DUF1297; Protein of unknown function DUF1246; KEGG: mac:MA3689 hypothetical protein. | Protein of unknown function DUF1297; Catalyzes the ATP- and formate-dependent formylation of 5- aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates. Belongs to the phosphohexose mutase family. | 0.921 |
Mthe_1218 | Mthe_0311 | Mthe_1218 | Mthe_0311 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: mac:MA3971 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Conserved hypothetical protein; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Belongs to the adenylate kinase family. AK6 subfamily. | 0.900 |
Mthe_1218 | Mthe_1099 | Mthe_1218 | Mthe_1099 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: mac:MA3971 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | PFAM: Protein of unknown function DUF1297; Protein of unknown function DUF1246; KEGG: mac:MA3689 hypothetical protein. | 0.939 |
Mthe_1218 | Mthe_1511 | Mthe_1218 | Mthe_1511 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: mac:MA3971 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | PFAM: AICARFT/IMPCHase bienzyme, formylation region; KEGG: mca:MCA1747 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase. | 0.999 |
Mthe_1218 | adk | Mthe_1218 | Mthe_1504 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: mac:MA3971 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.963 |
Mthe_1218 | guaAA | Mthe_1218 | Mthe_0166 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: mac:MA3971 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | GMP synthase, small subunit; Catalyzes the synthesis of GMP from XMP. | 0.646 |
Mthe_1218 | guaAB | Mthe_1218 | Mthe_0226 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: mac:MA3971 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.851 |
Mthe_1218 | hpt | Mthe_1218 | Mthe_1111 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: mac:MA3971 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily. | 0.984 |
Mthe_1218 | purP | Mthe_1218 | Mthe_0184 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: mac:MA3971 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Protein of unknown function DUF1297; Catalyzes the ATP- and formate-dependent formylation of 5- aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates. Belongs to the phosphohexose mutase family. | 0.941 |
Mthe_1218 | surE | Mthe_1218 | Mthe_1272 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: mac:MA3971 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 3'-nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.933 |
Mthe_1511 | Mthe_1099 | Mthe_1511 | Mthe_1099 | PFAM: AICARFT/IMPCHase bienzyme, formylation region; KEGG: mca:MCA1747 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase. | PFAM: Protein of unknown function DUF1297; Protein of unknown function DUF1246; KEGG: mac:MA3689 hypothetical protein. | 0.908 |
Mthe_1511 | Mthe_1218 | Mthe_1511 | Mthe_1218 | PFAM: AICARFT/IMPCHase bienzyme, formylation region; KEGG: mca:MCA1747 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase. | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: mac:MA3971 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.999 |
Mthe_1511 | adk | Mthe_1511 | Mthe_1504 | PFAM: AICARFT/IMPCHase bienzyme, formylation region; KEGG: mca:MCA1747 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.483 |