STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mthe_1500PFAM: protein of unknown function DUF92, transmembrane; KEGG: mac:MA1653 integral membrane protein. (391 aa)    
Predicted Functional Partners:
aroE
Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
       0.780
Mthe_1499
Undecaprenyl diphosphate synthase; KEGG: nph:NP4544A di-trans,poly-cis-decaprenylcistransferase 2; (Z)-prenyl diphosphate synthase 2; TIGRFAM: undecaprenyl diphosphate synthase; PFAM: Di-trans-poly-cis-decaprenylcistransferase.
     
 0.743
Mthe_1503
PFAM: glycoside hydrolase 15-related; KEGG: mac:MA1190 glucan 1,4-alpha-glucosidase.
       0.600
Mthe_1502
PFAM: Prephenate dehydrogenase; KEGG: mma:MM1275 prephenate dehydrogenase.
       0.505
rps3ae
PFAM: ribosomal protein S3Ae; KEGG: mbu:Mbur_2336 ribosomal protein S3Ae; Belongs to the eukaryotic ribosomal protein eS1 family.
 
     0.490
Mthe_1498
PFAM: Oligosaccharyl transferase, STT3 subunit; KEGG: mma:MM0647 oligosaccharyl transferase.
 
     0.475
Mthe_1704
PFAM: protein of unknown function DUF106, transmembrane; KEGG: mma:MM2152 hypothetical protein.
  
     0.407
Your Current Organism:
Methanothrix thermoacetophila
NCBI taxonomy Id: 349307
Other names: M. thermoacetophila PT, Methanosaeta thermophila PT, Methanothrix thermoacetophila PT, Methanothrix thermophila DSM 6194, Methanothrix thermophila PT
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