STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mthe_1667Protein of unknown function DUF127; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. (174 aa)    
Predicted Functional Partners:
Mthe_1666
PFAM: protein of unknown function DUF201; KEGG: mac:MA3870 hypothetical protein.
       0.680
Mthe_0694
PFAM: PUA domain containing protein; KEGG: mma:MM1408 archaeosine tRNA-ribosyltransferase.
 
     0.669
Mthe_0206
KEGG: nph:NP0908A nicotinamide-nucleotide adenylyltransferase 1; TIGRFAM: cytidyltransferase-related domain; nicotinamide-nucleotide adenylyltransferase; PFAM: cytidylyltransferase.
 
     0.662
tiaS
tRNA(Ile2) 2-agmatinylcytidine synthetase; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.
  
     0.640
rpl44e
LSU ribosomal protein L44E; Binds to the 23S rRNA.
  
     0.595
Mthe_0090
KEGG: mba:Mbar_A3470 hypothetical protein.
  
     0.570
Mthe_1323
Protein of unknown function DUF359; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).
  
    0.570
nac
Nascent polypeptide associated complex NAC; Contacts the emerging nascent chain on the ribosome. Belongs to the NAC-alpha family.
 
     0.556
eIF5A
Translation initiation factor 5A precursor (eIF-5A); Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.
  
    0.540
nep1
Suppressor Mra1; Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA.
  
   
 0.532
Your Current Organism:
Methanothrix thermoacetophila
NCBI taxonomy Id: 349307
Other names: M. thermoacetophila PT, Methanosaeta thermophila PT, Methanothrix thermoacetophila PT, Methanothrix thermophila DSM 6194, Methanothrix thermophila PT
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