STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pyrDBDihydroorotate dehydrogenase B, catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate. (306 aa)    
Predicted Functional Partners:
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
 
 0.998
pyrC
Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
 
 0.998
pyrF
Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
 
  
 0.984
pyrB
Aspartate carbamoyltransferase; COG0540F; TIGR00670; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
 
  
 0.982
pyrAA1
Carbamoylphosphate synthase small subunit; COG0505EF; Belongs to the CarA family.
 
  
 0.967
carB
Carbamoylphosphate synthase large subunit (split gene in MJ); COG0458EF.
 
 
 0.917
pyrP
Xanthine/uracil Permease; COG2233F.
  
  
 0.875
pheT
Phenylalanyl-tRNA synthetase, beta subunit; COG0072J; TIGR00472; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
  
  
 0.872
pyrAB
Carbamoylphosphate synthase large subunit (split gene in MJ); COG0458EF; Belongs to the CarB family.
  
 
 0.742
pyrAA2
Carbamoylphosphate synthase small subunit; COG0505EF; Belongs to the CarA family.
  
  
 0.726
Your Current Organism:
Leuconostoc citreum
NCBI taxonomy Id: 349519
Other names: L. citreum KM20, Leuconostoc citreum KM20, Leuconostoc citreum str. KM20, Leuconostoc citreum strain KM20
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