STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LCK_01110Guanosine polyphosphate pyrophosphohydrolase/synthetase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (745 aa)    
Predicted Functional Partners:
LCK_01174
GTP pyrophosphokinase; COG2357S.
    
 0.923
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
 0.918
gmk1
Guanylate kinase; COG0194F.
  
 
 0.916
gmk2
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
 
 0.916
pyk
Pyruvate kinase; COG0469G; TIGR01064; Belongs to the pyruvate kinase family.
   
 
 0.916
ppx1
Exopolyphosphatase; COG0248FP.
  
 
 0.913
ppx2
Exopolyphosphatase; COG0248FP.
  
 
 0.913
ppx3
Exopolyphosphatase; COG0248FP.
  
 
 0.913
nrdE
Ribonucleotide reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
     
 0.901
nrdD
Oxygen-sensitive ribonucleoside-triphosphate reductase; COG1328F.
     
 0.900
Your Current Organism:
Leuconostoc citreum
NCBI taxonomy Id: 349519
Other names: L. citreum KM20, Leuconostoc citreum KM20, Leuconostoc citreum str. KM20, Leuconostoc citreum strain KM20
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.