node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LCK_00240 | nadD | LCK_00240 | LCK_00395 | NAD-dependent protein deacetylase, SIR2 family; COG0846K. | Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.932 |
LCK_00240 | nadE | LCK_00240 | LCK_00494 | NAD-dependent protein deacetylase, SIR2 family; COG0846K. | NAD synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.924 |
LCK_00240 | ppnK | LCK_00240 | LCK_01173 | NAD-dependent protein deacetylase, SIR2 family; COG0846K. | Predicted sugar kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.921 |
LCK_00482 | ppnK | LCK_00482 | LCK_01173 | Hemolysin A; COG1189J; TIGR00478. | Predicted sugar kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.532 |
LCK_01174 | LCK_01175 | LCK_01174 | LCK_01175 | GTP pyrophosphokinase; COG2357S. | Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis. | 0.559 |
LCK_01174 | LCK_01176 | LCK_01174 | LCK_01176 | GTP pyrophosphokinase; COG2357S. | Methionine aminopeptidase. | 0.497 |
LCK_01174 | mgtE | LCK_01174 | LCK_01171 | GTP pyrophosphokinase; COG2357S. | Magnesium transporter; Acts as a magnesium transporter. | 0.547 |
LCK_01174 | ppnK | LCK_01174 | LCK_01173 | GTP pyrophosphokinase; COG2357S. | Predicted sugar kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.832 |
LCK_01174 | rluD2 | LCK_01174 | LCK_01172 | GTP pyrophosphokinase; COG2357S. | Pseudouridylate synthase, 23S RNA-specific; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 0.621 |
LCK_01175 | LCK_01174 | LCK_01175 | LCK_01174 | Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis. | GTP pyrophosphokinase; COG2357S. | 0.559 |
LCK_01175 | LCK_01176 | LCK_01175 | LCK_01176 | Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis. | Methionine aminopeptidase. | 0.768 |
LCK_01175 | mgtE | LCK_01175 | LCK_01171 | Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis. | Magnesium transporter; Acts as a magnesium transporter. | 0.414 |
LCK_01175 | ppnK | LCK_01175 | LCK_01173 | Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis. | Predicted sugar kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.559 |
LCK_01175 | rluD2 | LCK_01175 | LCK_01172 | Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis. | Pseudouridylate synthase, 23S RNA-specific; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 0.456 |
LCK_01176 | LCK_01174 | LCK_01176 | LCK_01174 | Methionine aminopeptidase. | GTP pyrophosphokinase; COG2357S. | 0.497 |
LCK_01176 | LCK_01175 | LCK_01176 | LCK_01175 | Methionine aminopeptidase. | Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis. | 0.768 |
LCK_01176 | ppnK | LCK_01176 | LCK_01173 | Methionine aminopeptidase. | Predicted sugar kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.497 |
alaS | ppnK | LCK_00467 | LCK_01173 | Alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity); Belongs to the class-II aminoacyl-tRNA synthetase family. | Predicted sugar kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.513 |
mgtE | LCK_01174 | LCK_01171 | LCK_01174 | Magnesium transporter; Acts as a magnesium transporter. | GTP pyrophosphokinase; COG2357S. | 0.547 |
mgtE | LCK_01175 | LCK_01171 | LCK_01175 | Magnesium transporter; Acts as a magnesium transporter. | Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis. | 0.414 |