node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
guaA | rimM | LCK_00589 | LCK_01210 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | RimM protein, required for 16S rRNA processing; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. | 0.926 |
guaA | rplA | LCK_00589 | LCK_01523 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | 0.966 |
guaA | rplM | LCK_00589 | LCK_01563 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.778 |
guaA | rplS | LCK_00589 | LCK_01245 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.879 |
guaA | rpsB | LCK_00589 | LCK_00990 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Ribosomal protein S2; COG0052J; TIGR01011; Belongs to the universal ribosomal protein uS2 family. | 0.679 |
guaA | rpsF | LCK_00589 | LCK_00169 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA. | 0.781 |
guaA | rpsL | LCK_00589 | LCK_01604 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy. | 0.792 |
guaA | rpsR | LCK_00589 | LCK_00171 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. | 0.498 |
guaA | trmD | LCK_00589 | LCK_01209 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | tRNA (guanine-N1)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. | 0.595 |
rimM | guaA | LCK_01210 | LCK_00589 | RimM protein, required for 16S rRNA processing; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.926 |
rimM | rplA | LCK_01210 | LCK_01523 | RimM protein, required for 16S rRNA processing; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. | Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | 0.906 |
rimM | rplM | LCK_01210 | LCK_01563 | RimM protein, required for 16S rRNA processing; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. | Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.918 |
rimM | rplS | LCK_01210 | LCK_01245 | RimM protein, required for 16S rRNA processing; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. | Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.938 |
rimM | rpsB | LCK_01210 | LCK_00990 | RimM protein, required for 16S rRNA processing; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. | Ribosomal protein S2; COG0052J; TIGR01011; Belongs to the universal ribosomal protein uS2 family. | 0.925 |
rimM | rpsF | LCK_01210 | LCK_00169 | RimM protein, required for 16S rRNA processing; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. | Ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA. | 0.920 |
rimM | rpsL | LCK_01210 | LCK_01604 | RimM protein, required for 16S rRNA processing; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. | Ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy. | 0.910 |
rimM | rpsP | LCK_01210 | LCK_01222 | RimM protein, required for 16S rRNA processing; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. | Ribosomal protein S16; COG0228J; TIGR00002; Belongs to the bacterial ribosomal protein bS16 family. | 0.950 |
rimM | rpsR | LCK_01210 | LCK_00171 | RimM protein, required for 16S rRNA processing; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. | Ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. | 0.912 |
rimM | trmD | LCK_01210 | LCK_01209 | RimM protein, required for 16S rRNA processing; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. | tRNA (guanine-N1)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. | 0.989 |
rplA | guaA | LCK_01523 | LCK_00589 | Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.966 |