node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HCH_00023 | HCH_05315 | HCH_00023 | HCH_05315 | Lauroyl/myristoyl acyltransferase; COG1560. | Predicted sugar phosphate isomerase involved in capsule formation; COG0794. | 0.724 |
HCH_00023 | kdtA | HCH_00023 | HCH_05997 | Lauroyl/myristoyl acyltransferase; COG1560. | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.975 |
HCH_00023 | lpxA | HCH_00023 | HCH_05239 | Lauroyl/myristoyl acyltransferase; COG1560. | acyl-[acyl-carrier-protein]--UDP-N- acetylglucosam ine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.698 |
HCH_00023 | lpxB | HCH_00023 | HCH_05238 | Lauroyl/myristoyl acyltransferase; COG1560. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.796 |
HCH_00023 | lpxC | HCH_00023 | HCH_05876 | Lauroyl/myristoyl acyltransferase; COG1560. | UDP-3-0-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.706 |
HCH_00023 | lpxD | HCH_00023 | HCH_05241 | Lauroyl/myristoyl acyltransferase; COG1560. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.779 |
HCH_00023 | lpxK | HCH_00023 | HCH_02704 | Lauroyl/myristoyl acyltransferase; COG1560. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.723 |
HCH_00023 | lpxL | HCH_00023 | HCH_01058 | Lauroyl/myristoyl acyltransferase; COG1560. | Lauroyl/myristoyl acyltransferase; Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A). | 0.925 |
HCH_00023 | rfaQ | HCH_00023 | HCH_01054 | Lauroyl/myristoyl acyltransferase; COG1560. | Lipopolysaccharide heptosyltransferase III, putative; TIGRFAMsMatches:TIGR02201. | 0.415 |
HCH_01056 | lpxL | HCH_01056 | HCH_01058 | Glycosyltransferase; COG0438. | Lauroyl/myristoyl acyltransferase; Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A). | 0.747 |
HCH_01056 | rfaQ | HCH_01056 | HCH_01054 | Glycosyltransferase; COG0438. | Lipopolysaccharide heptosyltransferase III, putative; TIGRFAMsMatches:TIGR02201. | 0.902 |
HCH_05315 | HCH_00023 | HCH_05315 | HCH_00023 | Predicted sugar phosphate isomerase involved in capsule formation; COG0794. | Lauroyl/myristoyl acyltransferase; COG1560. | 0.724 |
HCH_05315 | kdtA | HCH_05315 | HCH_05997 | Predicted sugar phosphate isomerase involved in capsule formation; COG0794. | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.892 |
HCH_05315 | lpxA | HCH_05315 | HCH_05239 | Predicted sugar phosphate isomerase involved in capsule formation; COG0794. | acyl-[acyl-carrier-protein]--UDP-N- acetylglucosam ine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.878 |
HCH_05315 | lpxB | HCH_05315 | HCH_05238 | Predicted sugar phosphate isomerase involved in capsule formation; COG0794. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.881 |
HCH_05315 | lpxC | HCH_05315 | HCH_05876 | Predicted sugar phosphate isomerase involved in capsule formation; COG0794. | UDP-3-0-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.882 |
HCH_05315 | lpxD | HCH_05315 | HCH_05241 | Predicted sugar phosphate isomerase involved in capsule formation; COG0794. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.872 |
HCH_05315 | lpxK | HCH_05315 | HCH_02704 | Predicted sugar phosphate isomerase involved in capsule formation; COG0794. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.891 |
HCH_05315 | lpxL | HCH_05315 | HCH_01058 | Predicted sugar phosphate isomerase involved in capsule formation; COG0794. | Lauroyl/myristoyl acyltransferase; Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A). | 0.759 |
HCH_05315 | rfaQ | HCH_05315 | HCH_01054 | Predicted sugar phosphate isomerase involved in capsule formation; COG0794. | Lipopolysaccharide heptosyltransferase III, putative; TIGRFAMsMatches:TIGR02201. | 0.710 |