node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HCH_01365 | HCH_02186 | HCH_01365 | HCH_02186 | Acetyl-CoA acetyltransferase; COG0183; Belongs to the thiolase-like superfamily. Thiolase family. | Acetyl-CoA acetyltransferase; COG0183; Belongs to the thiolase-like superfamily. Thiolase family. | 0.828 |
HCH_01365 | aceF | HCH_01365 | HCH_01273 | Acetyl-CoA acetyltransferase; COG0183; Belongs to the thiolase-like superfamily. Thiolase family. | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.910 |
HCH_01365 | acsA1 | HCH_01365 | HCH_04804 | Acetyl-CoA acetyltransferase; COG0183; Belongs to the thiolase-like superfamily. Thiolase family. | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.941 |
HCH_01365 | acsA2 | HCH_01365 | HCH_05074 | Acetyl-CoA acetyltransferase; COG0183; Belongs to the thiolase-like superfamily. Thiolase family. | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.941 |
HCH_01365 | glcB | HCH_01365 | HCH_01653 | Acetyl-CoA acetyltransferase; COG0183; Belongs to the thiolase-like superfamily. Thiolase family. | Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | 0.933 |
HCH_01365 | pta | HCH_01365 | HCH_04451 | Acetyl-CoA acetyltransferase; COG0183; Belongs to the thiolase-like superfamily. Thiolase family. | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.943 |
HCH_02186 | HCH_01365 | HCH_02186 | HCH_01365 | Acetyl-CoA acetyltransferase; COG0183; Belongs to the thiolase-like superfamily. Thiolase family. | Acetyl-CoA acetyltransferase; COG0183; Belongs to the thiolase-like superfamily. Thiolase family. | 0.828 |
HCH_02186 | aceF | HCH_02186 | HCH_01273 | Acetyl-CoA acetyltransferase; COG0183; Belongs to the thiolase-like superfamily. Thiolase family. | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.910 |
HCH_02186 | acsA1 | HCH_02186 | HCH_04804 | Acetyl-CoA acetyltransferase; COG0183; Belongs to the thiolase-like superfamily. Thiolase family. | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.941 |
HCH_02186 | acsA2 | HCH_02186 | HCH_05074 | Acetyl-CoA acetyltransferase; COG0183; Belongs to the thiolase-like superfamily. Thiolase family. | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.941 |
HCH_02186 | glcB | HCH_02186 | HCH_01653 | Acetyl-CoA acetyltransferase; COG0183; Belongs to the thiolase-like superfamily. Thiolase family. | Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | 0.933 |
HCH_02186 | pta | HCH_02186 | HCH_04451 | Acetyl-CoA acetyltransferase; COG0183; Belongs to the thiolase-like superfamily. Thiolase family. | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.943 |
HCH_02711 | aceF | HCH_02711 | HCH_01273 | Citrate synthase; COG0372; Belongs to the citrate synthase family. | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.621 |
HCH_02711 | ackA | HCH_02711 | HCH_04450 | Citrate synthase; COG0372; Belongs to the citrate synthase family. | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | 0.458 |
HCH_02711 | acsA1 | HCH_02711 | HCH_04804 | Citrate synthase; COG0372; Belongs to the citrate synthase family. | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.959 |
HCH_02711 | acsA2 | HCH_02711 | HCH_05074 | Citrate synthase; COG0372; Belongs to the citrate synthase family. | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.959 |
HCH_02711 | glcB | HCH_02711 | HCH_01653 | Citrate synthase; COG0372; Belongs to the citrate synthase family. | Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | 0.595 |
HCH_02711 | pta | HCH_02711 | HCH_04451 | Citrate synthase; COG0372; Belongs to the citrate synthase family. | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.957 |
HCH_02711 | scfA | HCH_02711 | HCH_05974 | Citrate synthase; COG0372; Belongs to the citrate synthase family. | Malic enzyme; COG0281. | 0.629 |
HCH_02711 | sucB1 | HCH_02711 | HCH_03685 | Citrate synthase; COG0372; Belongs to the citrate synthase family. | Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzyme COG0508. | 0.960 |