node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HCH_00001 | rlmL | HCH_00001 | HCH_04964 | Hypothetical protein. | Predicted SAM-dependent methyltransferase; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | 0.689 |
HCH_00001 | sun | HCH_00001 | HCH_00028 | Hypothetical protein. | Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.468 |
HCH_01037 | pnp | HCH_01037 | HCH_01244 | Predicted membrane GTPase involved in stress response; COG1217. | Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase); Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.622 |
HCH_01037 | pyrG | HCH_01037 | HCH_01865 | Predicted membrane GTPase involved in stress response; COG1217. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.479 |
HCH_01037 | rlmL | HCH_01037 | HCH_04964 | Predicted membrane GTPase involved in stress response; COG1217. | Predicted SAM-dependent methyltransferase; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | 0.681 |
HCH_04736 | rlmL | HCH_04736 | HCH_04964 | 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; COG1187; Belongs to the pseudouridine synthase RsuA family. | Predicted SAM-dependent methyltransferase; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | 0.689 |
HCH_04736 | rsuA | HCH_04736 | HCH_02335 | 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; COG1187; Belongs to the pseudouridine synthase RsuA family. | 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; COG1187; Belongs to the pseudouridine synthase RsuA family. | 0.419 |
HCH_04736 | sun | HCH_04736 | HCH_00028 | 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; COG1187; Belongs to the pseudouridine synthase RsuA family. | Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.555 |
HCH_06234 | rlmL | HCH_06234 | HCH_04964 | Biotin-(acetyl-CoA carboxylase) ligase; COG0340. | Predicted SAM-dependent methyltransferase; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | 0.652 |
argS | pnp | HCH_01116 | HCH_01244 | arginyl-tRNA synthetase; TIGRFAMsMatches:TIGR00456. | Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase); Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.696 |
argS | pyrG | HCH_01116 | HCH_01865 | arginyl-tRNA synthetase; TIGRFAMsMatches:TIGR00456. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.872 |
argS | rlmL | HCH_01116 | HCH_04964 | arginyl-tRNA synthetase; TIGRFAMsMatches:TIGR00456. | Predicted SAM-dependent methyltransferase; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | 0.647 |
argS | sun | HCH_01116 | HCH_00028 | arginyl-tRNA synthetase; TIGRFAMsMatches:TIGR00456. | Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.710 |
argS | uppS | HCH_01116 | HCH_05248 | arginyl-tRNA synthetase; TIGRFAMsMatches:TIGR00456. | Undecaprenyl diphosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. | 0.403 |
pnp | HCH_01037 | HCH_01244 | HCH_01037 | Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase); Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | Predicted membrane GTPase involved in stress response; COG1217. | 0.622 |
pnp | argS | HCH_01244 | HCH_01116 | Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase); Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | arginyl-tRNA synthetase; TIGRFAMsMatches:TIGR00456. | 0.696 |
pnp | pyrG | HCH_01244 | HCH_01865 | Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase); Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.886 |
pnp | rlmL | HCH_01244 | HCH_04964 | Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase); Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | Predicted SAM-dependent methyltransferase; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | 0.761 |
pnp | sun | HCH_01244 | HCH_00028 | Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase); Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.470 |
pnp | uppS | HCH_01244 | HCH_05248 | Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase); Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | Undecaprenyl diphosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. | 0.823 |