node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HCH_05334 | ftsI | HCH_05334 | HCH_05889 | Actin-like ATPase involved in cell morphogenesis; COG1077. | Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | 0.719 |
HCH_05334 | mrdA | HCH_05334 | HCH_05843 | Actin-like ATPase involved in cell morphogenesis; COG1077. | Cell division protein FtsI/penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | 0.916 |
HCH_05334 | mreC | HCH_05334 | HCH_05333 | Actin-like ATPase involved in cell morphogenesis; COG1077. | Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape. | 0.995 |
HCH_05334 | murC | HCH_05334 | HCH_05882 | Actin-like ATPase involved in cell morphogenesis; COG1077. | UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.474 |
HCH_05334 | murD | HCH_05334 | HCH_05885 | Actin-like ATPase involved in cell morphogenesis; COG1077. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.411 |
HCH_05334 | murF | HCH_05334 | HCH_05887 | Actin-like ATPase involved in cell morphogenesis; COG1077. | UDP-N-acetylmuramyl pentapeptide synthase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.449 |
HCH_05334 | murG | HCH_05334 | HCH_05883 | Actin-like ATPase involved in cell morphogenesis; COG1077. | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.524 |
HCH_05334 | rlpA | HCH_05334 | HCH_05840 | Actin-like ATPase involved in cell morphogenesis; COG1077. | Lipoprotein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. | 0.503 |
HCH_05334 | rodA | HCH_05334 | HCH_05842 | Actin-like ATPase involved in cell morphogenesis; COG1077. | Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | 0.873 |
ftsI | HCH_05334 | HCH_05889 | HCH_05334 | Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | Actin-like ATPase involved in cell morphogenesis; COG1077. | 0.719 |
ftsI | ftsQ | HCH_05889 | HCH_05880 | Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | Cell division septal protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | 0.960 |
ftsI | mrdA | HCH_05889 | HCH_05843 | Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | Cell division protein FtsI/penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | 0.944 |
ftsI | mreC | HCH_05889 | HCH_05333 | Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape. | 0.848 |
ftsI | murC | HCH_05889 | HCH_05882 | Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.956 |
ftsI | murD | HCH_05889 | HCH_05885 | Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.991 |
ftsI | murF | HCH_05889 | HCH_05887 | Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | UDP-N-acetylmuramyl pentapeptide synthase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.967 |
ftsI | murG | HCH_05889 | HCH_05883 | Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.921 |
ftsI | rlpA | HCH_05889 | HCH_05840 | Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | Lipoprotein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. | 0.806 |
ftsI | rodA | HCH_05889 | HCH_05842 | Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | 0.975 |
ftsQ | ftsI | HCH_05880 | HCH_05889 | Cell division septal protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | 0.960 |