node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HCH_06100 | apaG | HCH_06100 | HCH_06102 | Uncharacterized small membrane protein; COG2363. | Uncharacterized protein affecting Mg2+/Co2+ transport; COG2967. | 0.618 |
HCH_06100 | apaH | HCH_06100 | HCH_06101 | Uncharacterized small membrane protein; COG2363. | Bis(5'-nucleosyl)-tetraphosphatase (symmetrical); Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | 0.773 |
HCH_06100 | ksgA | HCH_06100 | HCH_06103 | Uncharacterized small membrane protein; COG2363. | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.508 |
HCH_06100 | pdxA | HCH_06100 | HCH_06104 | Uncharacterized small membrane protein; COG2363. | 4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). | 0.510 |
HCH_06100 | rlmL | HCH_06100 | HCH_04964 | Uncharacterized small membrane protein; COG2363. | Predicted SAM-dependent methyltransferase; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | 0.467 |
HCH_06100 | rlmM | HCH_06100 | HCH_02278 | Uncharacterized small membrane protein; COG2363. | Predicted SAM-dependent methyltransferase; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily. | 0.725 |
HCH_06100 | slmA | HCH_06100 | HCH_06098 | Uncharacterized small membrane protein; COG2363. | Transcriptional regulator; Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions. | 0.566 |
HCH_06100 | surA | HCH_06100 | HCH_06105 | Uncharacterized small membrane protein; COG2363. | Parvulin-like peptidyl-prolyl isomerase; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation. | 0.408 |
apaG | HCH_06100 | HCH_06102 | HCH_06100 | Uncharacterized protein affecting Mg2+/Co2+ transport; COG2967. | Uncharacterized small membrane protein; COG2363. | 0.618 |
apaG | apaH | HCH_06102 | HCH_06101 | Uncharacterized protein affecting Mg2+/Co2+ transport; COG2967. | Bis(5'-nucleosyl)-tetraphosphatase (symmetrical); Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | 0.688 |
apaG | ksgA | HCH_06102 | HCH_06103 | Uncharacterized protein affecting Mg2+/Co2+ transport; COG2967. | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.950 |
apaG | pdxA | HCH_06102 | HCH_06104 | Uncharacterized protein affecting Mg2+/Co2+ transport; COG2967. | 4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). | 0.809 |
apaG | slmA | HCH_06102 | HCH_06098 | Uncharacterized protein affecting Mg2+/Co2+ transport; COG2967. | Transcriptional regulator; Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions. | 0.516 |
apaG | surA | HCH_06102 | HCH_06105 | Uncharacterized protein affecting Mg2+/Co2+ transport; COG2967. | Parvulin-like peptidyl-prolyl isomerase; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation. | 0.686 |
apaH | HCH_06100 | HCH_06101 | HCH_06100 | Bis(5'-nucleosyl)-tetraphosphatase (symmetrical); Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | Uncharacterized small membrane protein; COG2363. | 0.773 |
apaH | apaG | HCH_06101 | HCH_06102 | Bis(5'-nucleosyl)-tetraphosphatase (symmetrical); Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | Uncharacterized protein affecting Mg2+/Co2+ transport; COG2967. | 0.688 |
apaH | ksgA | HCH_06101 | HCH_06103 | Bis(5'-nucleosyl)-tetraphosphatase (symmetrical); Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.611 |
apaH | pdxA | HCH_06101 | HCH_06104 | Bis(5'-nucleosyl)-tetraphosphatase (symmetrical); Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | 4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). | 0.606 |
apaH | slmA | HCH_06101 | HCH_06098 | Bis(5'-nucleosyl)-tetraphosphatase (symmetrical); Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | Transcriptional regulator; Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions. | 0.566 |
apaH | surA | HCH_06101 | HCH_06105 | Bis(5'-nucleosyl)-tetraphosphatase (symmetrical); Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | Parvulin-like peptidyl-prolyl isomerase; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation. | 0.598 |