STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Amuc_0075PFAM: PfkB domain protein; KEGG: tex:Teth514_1119 PfkB domain protein. (355 aa)    
Predicted Functional Partners:
pfp
Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
 
 
 0.930
pgi
PFAM: phosphoglucose isomerase (PGI); KEGG: mar:MAE_16590 glucose-6-phosphate isomerase; Belongs to the GPI family.
 
 
 0.925
Amuc_1870
Alpha-glucosidase; PFAM: glycoside hydrolase family 31; KEGG: gfo:GFO_2998 alpha-glucosidase; Belongs to the glycosyl hydrolase 31 family.
 
 
 0.913
nagB
Glucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
  
 
 0.912
Amuc_1245
PFAM: mannose-6-phosphate isomerase type I; KEGG: tex:Teth514_1319 mannose-6-phosphate isomerase, class I.
    
 0.909
Amuc_2116
PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: cpy:Cphy_1179 alcohol dehydrogenase zinc-binding domain protein.
  
 
 0.908
Amuc_0210
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family.
  
 
 0.904
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
  
 
 0.904
Amuc_1420
KEGG: sus:Acid_3433 hypothetical protein.
     
  0.900
fucI
L-fucose isomerase; Converts the aldose L-fucose into the corresponding ketose L- fuculose.
    
  0.804
Your Current Organism:
Akkermansia muciniphila
NCBI taxonomy Id: 349741
Other names: A. muciniphila ATCC BAA-835, Akkermansia muciniphila ATCC BAA-835, Akkermansia muciniphila Muc, Akkermansia muciniphila str. ATCC BAA-835, Akkermansia muciniphila strain ATCC BAA-835, Akkermansia sp. Muc
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