node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Amuc_1162 | gcvP | Amuc_1162 | Amuc_0448 | Threonine aldolase; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: cac:CAC3420 low specificity L-threonine aldolase. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.942 |
Amuc_1162 | glyA | Amuc_1162 | Amuc_1630 | Threonine aldolase; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: cac:CAC3420 low specificity L-threonine aldolase. | Sugar-phosphate isomerase, RpiB/LacA/LacB family; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.930 |
Amuc_1162 | kbl | Amuc_1162 | Amuc_0077 | Threonine aldolase; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: cac:CAC3420 low specificity L-threonine aldolase. | 2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. | 0.907 |
Amuc_1253 | Amuc_1689 | Amuc_1253 | Amuc_1689 | PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: aba:Acid345_3680 glutamate synthase (ferredoxin). | TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: gfo:GFO_1865 dihydrolipoamide dehydrogenase. | 0.895 |
Amuc_1253 | Amuc_2066 | Amuc_1253 | Amuc_2066 | PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: aba:Acid345_3680 glutamate synthase (ferredoxin). | PFAM: Proline dehydrogenase; Aldehyde Dehydrogenase_; KEGG: pcu:pc0033 putative bifunctional protein (proline dehydrogenase and delta-1-pyrroline-5-carboxylate dehydrogenase); Belongs to the aldehyde dehydrogenase family. | 0.965 |
Amuc_1253 | gcvH | Amuc_1253 | Amuc_0447 | PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: aba:Acid345_3680 glutamate synthase (ferredoxin). | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.873 |
Amuc_1253 | gcvP | Amuc_1253 | Amuc_0448 | PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: aba:Acid345_3680 glutamate synthase (ferredoxin). | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.956 |
Amuc_1253 | gcvT | Amuc_1253 | Amuc_0446 | PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: aba:Acid345_3680 glutamate synthase (ferredoxin). | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.884 |
Amuc_1253 | glyA | Amuc_1253 | Amuc_1630 | PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: aba:Acid345_3680 glutamate synthase (ferredoxin). | Sugar-phosphate isomerase, RpiB/LacA/LacB family; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.491 |
Amuc_1689 | Amuc_1253 | Amuc_1689 | Amuc_1253 | TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: gfo:GFO_1865 dihydrolipoamide dehydrogenase. | PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: aba:Acid345_3680 glutamate synthase (ferredoxin). | 0.895 |
Amuc_1689 | Amuc_2066 | Amuc_1689 | Amuc_2066 | TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: gfo:GFO_1865 dihydrolipoamide dehydrogenase. | PFAM: Proline dehydrogenase; Aldehyde Dehydrogenase_; KEGG: pcu:pc0033 putative bifunctional protein (proline dehydrogenase and delta-1-pyrroline-5-carboxylate dehydrogenase); Belongs to the aldehyde dehydrogenase family. | 0.876 |
Amuc_1689 | Amuc_2144 | Amuc_1689 | Amuc_2144 | TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: gfo:GFO_1865 dihydrolipoamide dehydrogenase. | Hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.401 |
Amuc_1689 | gcvH | Amuc_1689 | Amuc_0447 | TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: gfo:GFO_1865 dihydrolipoamide dehydrogenase. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.992 |
Amuc_1689 | gcvP | Amuc_1689 | Amuc_0448 | TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: gfo:GFO_1865 dihydrolipoamide dehydrogenase. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.948 |
Amuc_1689 | gcvT | Amuc_1689 | Amuc_0446 | TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: gfo:GFO_1865 dihydrolipoamide dehydrogenase. | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.968 |
Amuc_1689 | glyA | Amuc_1689 | Amuc_1630 | TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: gfo:GFO_1865 dihydrolipoamide dehydrogenase. | Sugar-phosphate isomerase, RpiB/LacA/LacB family; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.942 |
Amuc_2066 | Amuc_1253 | Amuc_2066 | Amuc_1253 | PFAM: Proline dehydrogenase; Aldehyde Dehydrogenase_; KEGG: pcu:pc0033 putative bifunctional protein (proline dehydrogenase and delta-1-pyrroline-5-carboxylate dehydrogenase); Belongs to the aldehyde dehydrogenase family. | PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: aba:Acid345_3680 glutamate synthase (ferredoxin). | 0.965 |
Amuc_2066 | Amuc_1689 | Amuc_2066 | Amuc_1689 | PFAM: Proline dehydrogenase; Aldehyde Dehydrogenase_; KEGG: pcu:pc0033 putative bifunctional protein (proline dehydrogenase and delta-1-pyrroline-5-carboxylate dehydrogenase); Belongs to the aldehyde dehydrogenase family. | TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: gfo:GFO_1865 dihydrolipoamide dehydrogenase. | 0.876 |
Amuc_2066 | gcvH | Amuc_2066 | Amuc_0447 | PFAM: Proline dehydrogenase; Aldehyde Dehydrogenase_; KEGG: pcu:pc0033 putative bifunctional protein (proline dehydrogenase and delta-1-pyrroline-5-carboxylate dehydrogenase); Belongs to the aldehyde dehydrogenase family. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.870 |
Amuc_2066 | gcvP | Amuc_2066 | Amuc_0448 | PFAM: Proline dehydrogenase; Aldehyde Dehydrogenase_; KEGG: pcu:pc0033 putative bifunctional protein (proline dehydrogenase and delta-1-pyrroline-5-carboxylate dehydrogenase); Belongs to the aldehyde dehydrogenase family. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.883 |