STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Amuc_0862TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: ATP-cone domain protein; KEGG: wsu:WS0684 anaerobic ribonucleoside triphosphate reductase. (698 aa)    
Predicted Functional Partners:
Amuc_0860
TIGRFAM: anaerobic ribonucleoside-triphosphate reductase activating protein; PFAM: Radical SAM domain protein; KEGG: cco:CCC13826_1899 anaerobic ribonucleoside-triphosphate reductase activating protein.
  
 0.983
queE
Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
  
 
 0.921
Amuc_0861
KEGG: cff:CFF8240_0023 hypothetical protein.
 
     0.914
Amuc_1580
PFAM: nucleoside diphosphate kinase; KEGG: bfs:BF3733 putative nucleoside diphosphate kinase; Belongs to the NDK family.
     
 0.909
pyrG
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
     
 0.906
Amuc_0431
KEGG: lbl:LBL_4267 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family.
     
  0.900
Amuc_0571
TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: sth:STH3231 hypothetical protein.
     
  0.900
Amuc_1847
KEGG: chu:CHU_2101 deoxyguanosinetriphosphate triphosphohydrolase; TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase; SMART: metal-dependent phosphohydrolase HD region.
     
  0.900
ribBA
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
    
  0.803
folE2
Protein of unknown function DUF198; Converts GTP to 7,8-dihydroneopterin triphosphate.
     
  0.800
Your Current Organism:
Akkermansia muciniphila
NCBI taxonomy Id: 349741
Other names: A. muciniphila ATCC BAA-835, Akkermansia muciniphila ATCC BAA-835, Akkermansia muciniphila Muc, Akkermansia muciniphila str. ATCC BAA-835, Akkermansia muciniphila strain ATCC BAA-835, Akkermansia sp. Muc
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