STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Amuc_1007Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: bth:BT_0729 transcriptional regulator. (298 aa)    
Predicted Functional Partners:
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.846
Amuc_1805
PFAM: Antibiotic biosynthesis monooxygenase; KEGG: bfs:BF2126 putative flavoredoxin.
 
   
 0.753
Amuc_1806
PFAM: Carboxymuconolactone decarboxylase; KEGG: bfr:BF1907 hypothetical protein.
 
 
 0.610
Amuc_1006
KEGG: rfr:Rfer_2445 aldo/keto reductase.
       0.532
Amuc_1005
KEGG: afw:Anae109_3206 aldo/keto reductase.
       0.463
Amuc_0278
PFAM: NUDIX hydrolase; KEGG: bth:BT_0791 hypothetical protein.
  
   
 0.457
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
 
   
 0.443
Amuc_1002
PFAM: Carboxymuconolactone decarboxylase; KEGG: gur:Gura_4370 cupin 2, conserved barrel domain protein.
 
   
 0.422
Amuc_1010
Response regulator receiver protein; PFAM: LytTr DNA-binding region; KEGG: bfr:BF2958 putative two-component system response regulator.
  
   
 0.406
Amuc_0624
PFAM: regulatory protein GntR HTH; KEGG: ooe:OEOE_0226 transcriptional regulator.
   
  
 0.400
Your Current Organism:
Akkermansia muciniphila
NCBI taxonomy Id: 349741
Other names: A. muciniphila ATCC BAA-835, Akkermansia muciniphila ATCC BAA-835, Akkermansia muciniphila Muc, Akkermansia muciniphila str. ATCC BAA-835, Akkermansia muciniphila strain ATCC BAA-835, Akkermansia sp. Muc
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