STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Amuc_1026Peptidylprolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (167 aa)    
Predicted Functional Partners:
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
  
 
 0.931
htpG
Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity.
  
 0.755
Amuc_0576
PFAM: peptidase M16 domain protein; KEGG: mmr:Mmar10_2605 peptidase M16 domain protein.
   
  
 0.613
Amuc_0371
KEGG: dol:Dole_0790 two component regulator propeller domain protein.
      
 0.602
Amuc_0006
KEGG: cyb:CYB_1660 lipoprotein, putative.
      
 0.600
Amuc_0789
Hypothetical protein; KEGG: dme:Dmel_CG8715 lingerer.
      
 0.600
Amuc_0837
Hypothetical protein; KEGG: rba:RB763 iduronate-2-sulfatase.
      
 0.600
Amuc_1333
KEGG: ddi:DDBDRAFT_0188625 hypothetical protein.
      
 0.600
Amuc_2165
KEGG: yli:YALI0F28281g hypothetical protein.
      
 0.600
Amuc_0808
KEGG: hch:HCH_02648 ATP-dependent helicase HrpA; TIGRFAM: ATP-dependent helicase HrpA; PFAM: helicase domain protein; helicase-associated domain protein; protein of unknown function DUF1605; SMART: DEAD-like helicases.
   
 0.570
Your Current Organism:
Akkermansia muciniphila
NCBI taxonomy Id: 349741
Other names: A. muciniphila ATCC BAA-835, Akkermansia muciniphila ATCC BAA-835, Akkermansia muciniphila Muc, Akkermansia muciniphila str. ATCC BAA-835, Akkermansia muciniphila strain ATCC BAA-835, Akkermansia sp. Muc
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