STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Coexpression
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[Homology]
Score
ahcYAdenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (471 aa)    
Predicted Functional Partners:
Amuc_1961
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.937
Amuc_1688
PFAM: amidohydrolase; Amidohydrolase 3; KEGG: dde:Dde_1812 atrazine chlorohydrolase.
 
 
 0.917
Amuc_0818
KEGG: lpn:lpg2172 adenosylhomocysteinase.
  
  
  0.915
Amuc_0790
O-acetylhomoserine/O-acetylserine sulfhydrylase; KEGG: bfs:BF3351 putative cysteine biosynthesis related protein; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein.
     
 0.903
Amuc_2013
O-acetylhomoserine/O-acetylserine sulfhydrylase; KEGG: bvu:BVU_2710 O-acetylhomoserine (thiol)-lyase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; DegT/DnrJ/EryC1/StrS aminotransferase.
     
 0.903
Amuc_1798
PFAM: aminotransferase class I and II; KEGG: bth:BT_1398 putative aminotransferase B.
     
  0.900
Amuc_2102
PFAM: aminotransferase class I and II; KEGG: bfs:BF0911 putative aminotransferase.
     
  0.900
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
 
 0.871
Amuc_1301
TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: cpy:Cphy_0011 cysteine synthase A.
  
 0.820
Amuc_2014
TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: cpy:Cphy_0011 cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
 0.820
Your Current Organism:
Akkermansia muciniphila
NCBI taxonomy Id: 349741
Other names: A. muciniphila ATCC BAA-835, Akkermansia muciniphila ATCC BAA-835, Akkermansia muciniphila Muc, Akkermansia muciniphila str. ATCC BAA-835, Akkermansia muciniphila strain ATCC BAA-835, Akkermansia sp. Muc
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