STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Amuc_1543KEGG: cya:CYA_0477 formate acetyltransferase; TIGRFAM: formate acetyltransferase; PFAM: formate C-acetyltransferase glycine radical; pyruvate formate-lyase PFL. (755 aa)    
Predicted Functional Partners:
Amuc_1542
Pyruvate formate-lyase activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family.
  
 0.995
Amuc_0799
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: mar:MAE_38140 pyruvate-flavodoxin oxidoreductase.
    
 0.967
gpmA
Phosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
    
 0.933
Amuc_1428
PFAM: phosphate acetyl/butaryl transferase; KEGG: tte:TTE1482 phosphotransacetylase.
   
 
 0.920
Amuc_2106
PFAM: malic protein domain protein; malic protein NAD-binding; KEGG: dde:Dde_3637 malate dehydrogenase (oxaloacetate decarboxylating) (NADP+).
   
 
 0.920
Amuc_0431
KEGG: lbl:LBL_4267 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family.
   
 
 0.917
Amuc_0885
PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; KEGG: ttj:TTHA0184 branched-chain alpha-keto acid dehydrogenase subunit E2.
   
 
 0.912
Amuc_0947
PFAM: biotin/lipoyl attachment domain-containing protein; E3 binding domain protein; KEGG: nwi:Nwi_1816 dihydrolipoamide acetyltransferase, long form.
   
 
 0.912
Amuc_1689
TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: gfo:GFO_1865 dihydrolipoamide dehydrogenase.
     
 0.911
Amuc_0214
PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: bja:bll7286 pyruvate dehydrogenase; Belongs to the TPP enzyme family.
     
 0.908
Your Current Organism:
Akkermansia muciniphila
NCBI taxonomy Id: 349741
Other names: A. muciniphila ATCC BAA-835, Akkermansia muciniphila ATCC BAA-835, Akkermansia muciniphila Muc, Akkermansia muciniphila str. ATCC BAA-835, Akkermansia muciniphila strain ATCC BAA-835, Akkermansia sp. Muc
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