STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mflv_09485'-nucleotidase / 3'-nucleotidase; PFAM: Survival protein SurE; KEGG: msm:MSMEG_6820 acid phosphatase SurE. (261 aa)    
Predicted Functional Partners:
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
    
 0.954
Mflv_4842
Thymidine phosphorylase; KEGG: mmc:Mmcs_1232 pyrimidine-nucleoside phosphorylase; TIGRFAM: pyrimidine-nucleoside phosphorylase; PFAM: glycosyl transferase, family 3; Pyrimidine nucleoside phosphorylase, C-terminal domain.
    
 0.922
purH
KEGG: mva:Mvan_4856 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: MGS domain protein; AICARFT/IMPCHase bienzyme, formylation region.
    
 0.921
Mflv_2359
Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
 
  
 0.921
pyrH
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
    
 0.921
cmk
KEGG: mmc:Mmcs_2928 cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region.
    
 0.920
Mflv_4662
PFAM: NUDIX hydrolase; KEGG: mva:Mvan_1805 NUDIX hydrolase.
  
 
  0.919
pyrF
TIGRFAM: orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase; KEGG: mmc:Mmcs_2368 orotidine 5'-phosphate decarboxylase subfamily 2; Belongs to the OMP decarboxylase family. Type 2 subfamily.
    
 0.918
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
    
 0.918
Mflv_3280
TIGRFAM: competence/damage-inducible protein CinA; PFAM: molybdopterin binding domain; CinA domain protein; KEGG: mmc:Mmcs_2707 competence-damaged protein; Belongs to the CinA family.
    
  0.916
Your Current Organism:
Mycolicibacterium gilvum
NCBI taxonomy Id: 350054
Other names: M. gilvum PYR-GCK, Mycobacterium flavescens ATCC 700033, Mycobacterium flavescens PYR-GCK, Mycobacterium gilvum PYR-GCK, Mycolicibacterium gilvum PYR-GCK
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