node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Mflv_1848 | Mflv_2975 | Mflv_1848 | Mflv_2975 | PFAM: Polyprenyl synthetase; KEGG: mmc:Mmcs_5074 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | Geranylgeranyl-diphosphate synthase; PFAM: Polyprenyl synthetase; KEGG: mva:Mvan_3536 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 0.916 |
Mflv_1848 | dxs | Mflv_1848 | Mflv_3923 | PFAM: Polyprenyl synthetase; KEGG: mmc:Mmcs_5074 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | 0.503 |
Mflv_1848 | fni | Mflv_1848 | Mflv_4187 | PFAM: Polyprenyl synthetase; KEGG: mmc:Mmcs_5074 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | Isopentenyl-diphosphate delta-isomerase, type 2; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). | 0.928 |
Mflv_1848 | idi | Mflv_1848 | Mflv_1842 | PFAM: Polyprenyl synthetase; KEGG: mmc:Mmcs_5074 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | Isopentenyl-diphosphate delta-isomerase; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP). | 0.961 |
Mflv_1848 | ispH | Mflv_1848 | Mflv_2079 | PFAM: Polyprenyl synthetase; KEGG: mmc:Mmcs_5074 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.935 |
Mflv_2975 | Mflv_1848 | Mflv_2975 | Mflv_1848 | Geranylgeranyl-diphosphate synthase; PFAM: Polyprenyl synthetase; KEGG: mva:Mvan_3536 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | PFAM: Polyprenyl synthetase; KEGG: mmc:Mmcs_5074 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 0.916 |
Mflv_2975 | dxs | Mflv_2975 | Mflv_3923 | Geranylgeranyl-diphosphate synthase; PFAM: Polyprenyl synthetase; KEGG: mva:Mvan_3536 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | 0.573 |
Mflv_2975 | fni | Mflv_2975 | Mflv_4187 | Geranylgeranyl-diphosphate synthase; PFAM: Polyprenyl synthetase; KEGG: mva:Mvan_3536 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | Isopentenyl-diphosphate delta-isomerase, type 2; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). | 0.915 |
Mflv_2975 | idi | Mflv_2975 | Mflv_1842 | Geranylgeranyl-diphosphate synthase; PFAM: Polyprenyl synthetase; KEGG: mva:Mvan_3536 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | Isopentenyl-diphosphate delta-isomerase; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP). | 0.983 |
Mflv_2975 | ispH | Mflv_2975 | Mflv_2079 | Geranylgeranyl-diphosphate synthase; PFAM: Polyprenyl synthetase; KEGG: mva:Mvan_3536 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.943 |
Mflv_3561 | ispE | Mflv_3561 | Mflv_1934 | SSU ribosomal protein S1P; PFAM: RNA binding S1 domain protein; KEGG: mva:Mvan_3356 RNA binding S1 domain protein. | 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | 0.408 |
Mflv_3561 | ispH | Mflv_3561 | Mflv_2079 | SSU ribosomal protein S1P; PFAM: RNA binding S1 domain protein; KEGG: mva:Mvan_3356 RNA binding S1 domain protein. | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.916 |
dxr | dxs | Mflv_4083 | Mflv_3923 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | 0.995 |
dxr | idi | Mflv_4083 | Mflv_1842 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | Isopentenyl-diphosphate delta-isomerase; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP). | 0.690 |
dxr | ispE | Mflv_4083 | Mflv_1934 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | 0.948 |
dxr | ispF | Mflv_4083 | Mflv_1445 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). | 0.938 |
dxr | ispG | Mflv_4083 | Mflv_4081 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. | 0.986 |
dxr | ispH | Mflv_4083 | Mflv_2079 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.949 |
dxs | Mflv_1848 | Mflv_3923 | Mflv_1848 | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | PFAM: Polyprenyl synthetase; KEGG: mmc:Mmcs_5074 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 0.503 |
dxs | Mflv_2975 | Mflv_3923 | Mflv_2975 | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | Geranylgeranyl-diphosphate synthase; PFAM: Polyprenyl synthetase; KEGG: mva:Mvan_3536 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 0.573 |