STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mhpBExtradiol ring-cleavage dioxygenase, class III enzyme, subunit B; Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3-dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2-hydroxy-6- ketononatrienedioate, respectively; Belongs to the LigB/MhpB extradiol dioxygenase family. (315 aa)    
Predicted Functional Partners:
mhpA
Monooxygenase, FAD-binding protein; Catalyzes the insertion of one atom of molecular oxygen into position 2 of the phenyl ring of 3-(3-hydroxyphenyl)propionate (3-HPP) and hydroxycinnamic acid (3HCI).
 
 
 0.995
Mflv_2400
PFAM: alpha/beta hydrolase fold; KEGG: mmc:Mmcs_3787 alpha/beta hydrolase fold.
 
 
 0.994
Mflv_0545
PFAM: alpha/beta hydrolase fold; KEGG: mkm:Mkms_5609 alpha/beta hydrolase fold.
 
 
 0.941
Mflv_2487
KEGG: mmc:Mmcs_3688 hypothetical protein.
 
 
 0.924
Mflv_2404
PFAM: luciferase family protein; KEGG: mmc:Mmcs_3783 luciferase-like protein.
 
   
 0.917
Mflv_2403
KEGG: mmc:Mmcs_3784 fumarate reductase/succinate dehydrogenase flavoprotein-like protein.
 
     0.915
Mflv_2405
PFAM: short-chain dehydrogenase/reductase SDR; KEGG: mmc:Mmcs_3782 short-chain dehydrogenase/reductase SDR.
 
   
 0.882
Mflv_2406
KEGG: mmc:Mmcs_3781 hypothetical protein.
 
     0.877
Mflv_2407
PFAM: NADPH-dependent FMN reductase; KEGG: mmc:Mmcs_3780 NADPH-dependent FMN reductase.
  
  
 0.862
Mflv_2414
PFAM: alpha/beta hydrolase fold; KEGG: mmc:Mmcs_3771 alpha/beta hydrolase fold.
 
  
 0.824
Your Current Organism:
Mycolicibacterium gilvum
NCBI taxonomy Id: 350054
Other names: M. gilvum PYR-GCK, Mycobacterium flavescens ATCC 700033, Mycobacterium flavescens PYR-GCK, Mycobacterium gilvum PYR-GCK, Mycolicibacterium gilvum PYR-GCK
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