STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mvan_0486PFAM: aldehyde dehydrogenase; KEGG: mmc:Mmcs_1637 aldehyde dehydrogenase (NAD+); Belongs to the aldehyde dehydrogenase family. (486 aa)    
Predicted Functional Partners:
Mvan_0472
PFAM: dihydrodipicolinate synthetase; KEGG: mmc:Mmcs_1632 dihydrodipicolinate synthetase; Belongs to the DapA family.
  
 
 0.912
Mvan_0468
Gentisate 1,2-dioxygenase / 1-hydroxy-2-naphthoate dioxygenase; PFAM: Cupin domain protein; Cupin 2, conserved barrel domain protein; KEGG: mmc:Mmcs_1628 cupin 2, conserved barrel.
     
 0.903
Mvan_2218
PFAM: copper amine oxidase; KEGG: mmc:Mmcs_2000 amine oxidase (copper-containing).
  
 0.599
Mvan_3407
PFAM: copper amine oxidase; KEGG: cyb:CYB_2794 putative copper methylamine oxidase.
  
 0.599
kgd
2-oxoglutarate dehydrogenase E1 component; Shows three enzymatic activities that share a first common step, the attack of thiamine-PP on 2-oxoglutarate (alpha-ketoglutarate, KG), leading to the formation of an enamine-thiamine-PP intermediate upon decarboxylation. Thus, displays KGD activity, catalyzing the decarboxylation from five-carbon 2-oxoglutarate to four-carbon succinate semialdehyde (SSA). Also catalyzes C-C bond formation between the activated aldehyde formed after decarboxylation of alpha- ketoglutarate and the carbonyl of glyoxylate (GLX), to yield 2-hydroxy- 3-oxoadipate ( [...]
  
 0.574
Mvan_0484
PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; KEGG: mmc:Mmcs_1635 fumarate reductase/succinate dehydrogenase flavoprotein-like protein.
  
 
 0.571
fumC
Fumarase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 0.562
Mvan_2745
TIGRFAM: aconitate hydratase 1; PFAM: aconitate hydratase domain protein; KEGG: mmc:Mmcs_2449 aconitate hydratase 1.
  
 0.554
Mvan_0915
PFAM: Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase, NAD-binding; KEGG: mxa:MXAN_6987 fatty oxidation complex, alpha subunit.
  
 0.547
Mvan_5066
PFAM: Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase, NAD-binding; KEGG: mmc:Mmcs_4492 3-hydroxyacyl-CoA dehydrogenase, NAD-binding protein.
  
 0.547
Your Current Organism:
Mycolicibacterium vanbaalenii
NCBI taxonomy Id: 350058
Other names: M. vanbaalenii PYR-1, Mycobacterium sp. PYR-1, Mycobacterium vanbaalenii DSM 7251, Mycobacterium vanbaalenii PYR-1, Mycolicibacterium vanbaalenii DSM 7251, Mycolicibacterium vanbaalenii PYR-1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.