STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mvan_05974-hydroxy-2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. (338 aa)    
Predicted Functional Partners:
Mvan_0596
PFAM: Semialdehyde dehydrogenase, NAD - binding; KEGG: bur:Bcep18194_C7645 semialdehyde dehydrogenase, NAD - binding; Belongs to the acetaldehyde dehydrogenase family.
 
 0.999
Mvan_4392
Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.
 
 0.996
Mvan_5235
Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.
 
 0.996
Mvan_0595
PFAM: Hydratase/decarboxylase; KEGG: mta:Moth_1777 4-oxalocrotonate decarboxylase.
 
 
 0.995
Mvan_4393
PFAM: Hydratase/decarboxylase; KEGG: nfa:nfa33180 putative hydratase.
 
 
 0.985
Mvan_5236
PFAM: Hydratase/decarboxylase; KEGG: mmc:Mmcs_4661 4-oxalocrotonate decarboxylase.
 
 
 0.981
Mvan_5234
Pyruvate carboxyltransferase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
  
  
 
0.904
Mvan_4391
Pyruvate carboxyltransferase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
  
  
 
0.901
Mvan_0594
Transcriptional regulator, TetR family; PFAM: regulatory protein, TetR; KEGG: mpa:MAP1732c hypothetical protein.
       0.801
Mvan_0592
PFAM: alpha/beta hydrolase fold; KEGG: nfa:nfa4730 putative hydrolase.
 
  
 0.778
Your Current Organism:
Mycolicibacterium vanbaalenii
NCBI taxonomy Id: 350058
Other names: M. vanbaalenii PYR-1, Mycobacterium sp. PYR-1, Mycobacterium vanbaalenii DSM 7251, Mycobacterium vanbaalenii PYR-1, Mycolicibacterium vanbaalenii DSM 7251, Mycolicibacterium vanbaalenii PYR-1
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